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- W2287338601 abstract "A strain of chicken anaemia virus (CAV) was isolated on the lymphoblastoid cell line MSB1 from nine-week-old chickens, submitted to the laboratory for routine diagnostic investigation. The birds originated from a flock that exhibited increasing mortality within two weeks. Most of the investigated chickens showed gross pathological and histopathological lesions suggestive of both CAV and IBDV infections, such as paleness of the carcasses, subcutaneous and muscular haemorrhages throughout the body, bone marrow aplasia and thymic and bursal atrophy. After inoculation in the T-lymphoblastoid cell culture MSB1, initial signs of CPE, comprising enlargement of cells, growth slowdown and cell lysis were observed on the third passage. Investigation by PCR proved a presence of CAV DNA both in the thymuses of surveyed birds and in inoculated MSB1 cells. Together with CAV, coinfection with another infectious agent, suggestive for infectious bursal disease virus (IBDV) was detected. This is the first isolation of CAV in Bulgaria." @default.
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- W2287338601 date "2014-01-01" @default.
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- W2287338601 title "ISOLATION AND PCR IDENTIFICATION OF CHICKEN ANAEMIA VIRUS INFECTION IN BULGARIA" @default.
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