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- W2287369744 endingPage "69" @default.
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- W2287369744 abstract "Herpesviruses establish life-long infection in their hosts and maintain latent reservoirs for sporadic reactivation at peripheral sites, such as skin and mucosae. For herpes simplex virus infection, experimental studies in mice revealed that immediate protection against local reactivation or superinfection events in the skin relies on tissue resident memory T cells (TRM) rather than on their circulating counterparts. Recent evidence extends this notion to cytomegalovirus infection, which potently induces TRM cells in both mice and humans particularly in mucosal tissues that constitute important viral sanctuaries and are relevant entry sites for challenge and superinfections. The discovery unravels promising opportunities to exploit cytomegalovirus based vaccine vectors for the specific induction of tissue resident T cell subsets." @default.
- W2287369744 created "2016-06-24" @default.
- W2287369744 creator A5008537578 @default.
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- W2287369744 date "2016-02-01" @default.
- W2287369744 modified "2023-10-16" @default.
- W2287369744 title "Tissue-resident memory T cells in cytomegalovirus infection" @default.
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- W2287369744 doi "https://doi.org/10.1016/j.coviro.2016.01.014" @default.
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