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- W2287913574 abstract "Vascular dementia (VaD) is a common but heterogeneous condition in which there is a clear temporal relationship between thedementia and vascular disease. It may result from multiple large or small vessel strokes or a single strategic stroke. Subcorticalischaemic VaD includes multiple lacunes and subcortical arteriosclerotic encephalopathy (Binswanger's disease) and imagingshows multiple deep white matter lesions or leukoaraiosis. Large vessel disease may result in VaD by causing multiple corticaland subcortical strokes, while strategic stroke VaD is caused by a single stroke in a specific area of the brain. On the basis ofcinical features and imaging, definite, probable and possible VaD can be defined. Vascular risk factor reduction, particularlythe use of antihypertensive agents, remains the most important means to prevent VaD. Treatment is limited althoughacetylcholinesterase inhibitors may have value. Treating behavioural symptoms may be difficult and newer antipsychotics aswell as acetylcholinesterase inhibitor therapy should be considered." @default.
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- W2287913574 date "2003-11-01" @default.
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- W2287913574 title "Vascular dementia : review article" @default.
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