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• W2288100200 abstract "<h3>Objectives:</h3> To investigate the prevalence, antibiotic resistant profiles, and risk factors of early fecal carriage of <i>Enterococcus faecalis (E. faecalis)</i> and staphylococci among 150 healthy Saudi neonates born in a hospital setting in central Saudi Arabia. <h3>Methods:</h3> This prospective study was conducted in Al-Bukayriyah General Hospital, Qassim, Saudi Arabia, between June 2012 and January 2013. The <i>E. faecalis</i> and <i>Staphylococcus spp.</i> isolates were identified manually, and Vitek2 system was used for identity confirmation at the species level and minimum inhibitory concentration-susceptibility testing. <h3>Results:</h3> <i>Enterococcus faecalis</i> (n=73) and <i>Staphylococcus spp.</i> (n=18) were recovered. Unlike staphylococci, <i>E. faecalis</i> colonization did not significantly vary from day one up to 7 days of life, regardless of the type of feeding, but it was relatively higher among vaginally versus cesarean delivery. Both <i>Staphylococcus epidermidis</i> (<i>S. epidermidis</i>) and <i>Staphylococcus aureus</i> carriage increase as the body weight increases, and this difference was significant (<i>p</i>=0.025) for <i>S. epidermidis</i>. High-level resistance in Gentamycin among <i>E. faecalis</i> isolates was 25% and 11% to Streptomycin. Thirty percent of <i>S. epidermidis</i> were resistant to oxacillin and exhibited multidrug-resistant (MDR) patterns of 5 resistant markers, which were also observed among 2/5 (40%) of <i>Methicillin-resistant Staphylococcus aureus</i> isolates. <h3>Conclusion:</h3> <i>Enterococcus faecalis</i> did not significantly vary in relation to type of delivery, age up to 7 days, and type of feeding. The neonatal fecal carriage of MDR isolates should be considered as a crucial reservoir to the further spread of antimicrobial resistance genes among hospitals, cross infections, and the community." @default.
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• W2288100200 date "2016-03-01" @default.
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• W2288100200 title "Prevalence and risk factors of early fecal carriage of <i>Enterococcus faecalis</i> and <i>Staphylococcus spp</i> and their antimicrobial resistant patterns among healthy neonates born in a hospital setting in central Saudi Arabia" @default.
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• W2288100200 doi "https://doi.org/10.15537/smj.2016.3.13871" @default.
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