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- W2288147668 abstract "6006 Background: Clinical trials testing the validity of SNB in BC will not mature for several years, yet SNB has already been adopted as routine in many settings. Using a population-based cohort of new-onset BC pts in Los Angeles County, we examined the use and patient-, hospital-, and provider-level predictors of use of SNB and SNB-only (i.e. without completion dissection). Methods: From 4/1/00 to 11/30/00, we identified 1716 eligible new onset BC pts and all their available breast-related procedures using population-based tumor registry rapid case ascertainment (RCA). Of these, 1105 (64%) had any axillary excisional procedure. We excluded 138 with mastectomy as the first therapeutic procedure, leaving 967 in the RCA cohort. 489 of these pts provided additional information about their surgeons (self-report cohort). Multivariate logistic regression of SNB and separately of SNB-only was used to assess the influence of patient (age, race-ethnicity) and hospital (ownership, teaching, total bed number, and participation in SNB-clinical-trial) variables. Surgeon BC case volume (BCV) and gender were also examined for the self-report cohort. We adjusted for clustering of pts within hospitals (and within providers for the self-report cohort). Results: Use of SNB and SNB-only were prevalent (RCA cohort: 42% and 22%; self-report cohort: 46% and 23%). Odds ratios for use of SNB were lower for Blacks (0.35**), Hispanics (0.53*), older pts (0.97**), and pts not in a clinical-trial-hospital (5.8**). Odds ratio for use of SNB-only were also lower for smaller (1.004**) and teaching hospitals (0.22*). Results were similar for the self-report cohort. Surgeon BCV also predicted receipt of SNB and SNB-only. (OR 1.04–1.07**). Conclusions: Despite the absence of completed trials assessing the validity of SNB in the community, dissemination of the procedure has been extensive. Minority and elderly patients appear to be receiving SNB and SNB-only at rates lower than others. These data suggest observed disparities in care may occur as early as the initial diffusion of a new technology. * p ≤ 0.05; ** p ≤ 0.01 Author Disclosure Employment or Leadership Consultant or Advisory Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration National Cancer Institute" @default.
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- W2288147668 date "2004-07-15" @default.
- W2288147668 modified "2023-09-27" @default.
- W2288147668 title "Predictors of use of sentinel lymph node biopsy (SNB) in a population-based cohort of breast cancer (BC) patients (pts)" @default.
- W2288147668 doi "https://doi.org/10.1200/jco.2004.22.90140.6006" @default.
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