FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2288332502> ?p ?o ?g. }

• W2288332502 endingPage "829" @default.
• W2288332502 startingPage "823" @default.
• W2288332502 abstract "Abstract Background: Many epidemiologic studies are using metabolomics to discover markers of carcinogenesis. However, limited data are available on the influence of pre-analytic blood collection factors on metabolite measurement. Methods: We quantified 166 metabolites in archived plasma from 423 Health Professionals Follow-up Study and Nurses' Health Study participants using liquid chromatography–tandem mass spectrometry (LC-MS). We compared multivariable-adjusted geometric mean metabolite LC-MS peak areas across fasting time, season of blood collection, and time of day of blood collection categories. Results: The majority of metabolites (160 of 166 metabolites) had geometric mean peak areas that were within 15% comparing samples donated after fasting 9 to 12 versus ≥13 hours; greater differences were observed in samples donated after fasting ≤4 hours. Metabolite peak areas generally were similar across season of blood collection, although levels of certain metabolites (e.g., bile acids and purines/pyrimidines) tended to be different in the summer versus winter months. After adjusting for fasting status, geometric mean peak areas for bile acids and vitamins, but not other metabolites, differed by time of day of blood collection. Conclusion: Fasting, season of blood collection, and time of day of blood collection were not important sources of variability in measurements of most metabolites in our study. However, considering blood collection variables in the design or analysis of studies may be important for certain specific metabolites, particularly bile acids, purines/pyrimidines, and vitamins. Impact: These results may be useful for investigators formulating analysis plans for epidemiologic metabolomics studies, including determining which metabolites to a priori exclude from analyses. Cancer Epidemiol Biomarkers Prev; 25(5); 823–9. ©2016 AACR." @default.
• W2288332502 created "2016-06-24" @default.
• W2288332502 creator A5047496278 @default.
• W2288332502 creator A5057221073 @default.
• W2288332502 creator A5068795567 @default.
• W2288332502 creator A5070896103 @default.
• W2288332502 creator A5072226926 @default.
• W2288332502 creator A5074259922 @default.
• W2288332502 creator A5078859928 @default.
• W2288332502 creator A5089324682 @default.
• W2288332502 date "2016-05-01" @default.
• W2288332502 modified "2023-10-13" @default.
• W2288332502 title "Impact of Pre-analytic Blood Sample Collection Factors on Metabolomics" @default.
• W2288332502 cites W1979246104 @default.
• W2288332502 cites W1986202285 @default.
• W2288332502 cites W1996559176 @default.
• W2288332502 cites W2029742084 @default.
• W2288332502 cites W2036689171 @default.
• W2288332502 cites W2043615829 @default.
• W2288332502 cites W2055157189 @default.
• W2288332502 cites W2069376956 @default.
• W2288332502 cites W2078810890 @default.
• W2288332502 cites W2087400481 @default.
• W2288332502 cites W2104132854 @default.
• W2288332502 cites W2122100237 @default.
• W2288332502 cites W2129246819 @default.
• W2288332502 cites W2134167892 @default.
• W2288332502 cites W2158610710 @default.
• W2288332502 cites W2333494242 @default.
• W2288332502 doi "https://doi.org/10.1158/1055-9965.epi-15-1206" @default.
• W2288332502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4873428" @default.
• W2288332502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26941367" @default.
• W2288332502 hasPublicationYear "2016" @default.
• W2288332502 type Work @default.
• W2288332502 sameAs 2288332502 @default.
• W2288332502 citedByCount "42" @default.
• W2288332502 countsByYear W22883325022016 @default.
• W2288332502 countsByYear W22883325022017 @default.
• W2288332502 countsByYear W22883325022018 @default.
• W2288332502 countsByYear W22883325022019 @default.
• W2288332502 countsByYear W22883325022020 @default.
• W2288332502 countsByYear W22883325022021 @default.
• W2288332502 countsByYear W22883325022022 @default.
• W2288332502 countsByYear W22883325022023 @default.
• W2288332502 crossrefType "journal-article" @default.
• W2288332502 hasAuthorship W2288332502A5047496278 @default.
• W2288332502 hasAuthorship W2288332502A5057221073 @default.
• W2288332502 hasAuthorship W2288332502A5068795567 @default.
• W2288332502 hasAuthorship W2288332502A5070896103 @default.
• W2288332502 hasAuthorship W2288332502A5072226926 @default.
• W2288332502 hasAuthorship W2288332502A5074259922 @default.
• W2288332502 hasAuthorship W2288332502A5078859928 @default.
• W2288332502 hasAuthorship W2288332502A5089324682 @default.
• W2288332502 hasBestOaLocation W22883325021 @default.
• W2288332502 hasConcept C126322002 @default.
• W2288332502 hasConcept C135870905 @default.
• W2288332502 hasConcept C185592680 @default.
• W2288332502 hasConcept C194828623 @default.
• W2288332502 hasConcept C21565614 @default.
• W2288332502 hasConcept C2777477808 @default.
• W2288332502 hasConcept C2994091943 @default.
• W2288332502 hasConcept C42407357 @default.
• W2288332502 hasConcept C43617362 @default.
• W2288332502 hasConcept C71924100 @default.
• W2288332502 hasConceptScore W2288332502C126322002 @default.
• W2288332502 hasConceptScore W2288332502C135870905 @default.
• W2288332502 hasConceptScore W2288332502C185592680 @default.
• W2288332502 hasConceptScore W2288332502C194828623 @default.
• W2288332502 hasConceptScore W2288332502C21565614 @default.
• W2288332502 hasConceptScore W2288332502C2777477808 @default.
• W2288332502 hasConceptScore W2288332502C2994091943 @default.
• W2288332502 hasConceptScore W2288332502C42407357 @default.
• W2288332502 hasConceptScore W2288332502C43617362 @default.
• W2288332502 hasConceptScore W2288332502C71924100 @default.
• W2288332502 hasFunder F4320309673 @default.
• W2288332502 hasFunder F4320332161 @default.
• W2288332502 hasFunder F4320337338 @default.
• W2288332502 hasFunder F4320337351 @default.
• W2288332502 hasIssue "5" @default.
• W2288332502 hasLocation W22883325021 @default.
• W2288332502 hasLocation W22883325022 @default.
• W2288332502 hasLocation W22883325023 @default.
• W2288332502 hasLocation W22883325024 @default.
• W2288332502 hasOpenAccess W2288332502 @default.
• W2288332502 hasPrimaryLocation W22883325021 @default.
• W2288332502 hasRelatedWork W2042603351 @default.
• W2288332502 hasRelatedWork W2098617576 @default.
• W2288332502 hasRelatedWork W2174192751 @default.
• W2288332502 hasRelatedWork W2288332502 @default.
• W2288332502 hasRelatedWork W2401362214 @default.
• W2288332502 hasRelatedWork W2749646273 @default.
• W2288332502 hasRelatedWork W3019465949 @default.
• W2288332502 hasRelatedWork W3024509095 @default.
• W2288332502 hasRelatedWork W3027992916 @default.
• W2288332502 hasRelatedWork W423371831 @default.
• W2288332502 hasVolume "25" @default.
• W2288332502 isParatext "false" @default.
• W2288332502 isRetracted "false" @default.

• next