FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2288363860> ?p ?o ?g. }

• W2288363860 abstract "Abstract Mitochondria play key roles in cellular energy generation and lifespan of most eukaryotes. To understand the functions of four nuclear-encoded genes predicted to be related to the maintenance of mitochondrial morphology and function in Aspergillus nidulans , systematic characterization was carried out. The deletion and overexpression mutants of aodA , dnmA , mnSOD and pimA encoding alternative oxidase, dynamin related protein, manganese superoxide dismutase and Lon protease, respectively, were generated and examined for their growth, stress tolerances, respiration, autolysis, cell death, sterigmatocystin production, hyphal morphology and size and mitochondrial superoxide production as well as development. Overall, genetic manipulation of these genes had less effect on cellular physiology and ageing in A. nidulans than that of their homologs in another fungus Podospora anserina with a well-characterized senescence. The observed interspecial phenotypic differences can be explained by the dissimilar intrinsic stabilities of the mitochondrial genomes in A. nidulans and P. anserina . Furthermore, the marginally altered phenotypes observed in A. nidulans mutants indicate the presence of effective compensatory mechanisms for the complex networks of mitochondrial defense and quality control. Importantly, these findings can be useful for developing novel platforms for heterologous protein production, or on new biocontrol and bioremediation technologies based on Aspergillus species." @default.
• W2288363860 created "2016-06-24" @default.
• W2288363860 creator A5004223061 @default.
• W2288363860 creator A5006445023 @default.
• W2288363860 creator A5011420293 @default.
• W2288363860 creator A5026374518 @default.
• W2288363860 creator A5033824240 @default.
• W2288363860 creator A5057019119 @default.
• W2288363860 creator A5057058881 @default.
• W2288363860 creator A5065392518 @default.
• W2288363860 creator A5082367364 @default.
• W2288363860 creator A5082856054 @default.
• W2288363860 creator A5084498555 @default.
• W2288363860 creator A5089298188 @default.
• W2288363860 date "2016-02-05" @default.
• W2288363860 modified "2023-09-27" @default.
• W2288363860 title "Characterization of the aodA, dnmA, mnSOD and pimA genes in Aspergillus nidulans" @default.
• W2288363860 cites W1751864219 @default.
• W2288363860 cites W1883731916 @default.
• W2288363860 cites W1977833682 @default.
• W2288363860 cites W1979713317 @default.
• W2288363860 cites W1980299910 @default.
• W2288363860 cites W1988491814 @default.
• W2288363860 cites W1989725886 @default.
• W2288363860 cites W1992229572 @default.
• W2288363860 cites W1998162530 @default.
• W2288363860 cites W2003919494 @default.
• W2288363860 cites W2009265018 @default.
• W2288363860 cites W2012507572 @default.
• W2288363860 cites W2014960139 @default.
• W2288363860 cites W2022161896 @default.
• W2288363860 cites W2024433713 @default.
• W2288363860 cites W2027773931 @default.
• W2288363860 cites W2029010506 @default.
• W2288363860 cites W2029312295 @default.
• W2288363860 cites W2032234589 @default.
• W2288363860 cites W2036412806 @default.
• W2288363860 cites W2042367738 @default.
• W2288363860 cites W2043843825 @default.
• W2288363860 cites W2045017146 @default.
• W2288363860 cites W2045444560 @default.
• W2288363860 cites W2047195096 @default.
• W2288363860 cites W2054604249 @default.
• W2288363860 cites W2054772311 @default.
• W2288363860 cites W2060081344 @default.
• W2288363860 cites W2061990870 @default.
• W2288363860 cites W2065659813 @default.
• W2288363860 cites W2069220256 @default.
• W2288363860 cites W2075514851 @default.
• W2288363860 cites W2076838980 @default.
• W2288363860 cites W2081626666 @default.
• W2288363860 cites W2082084296 @default.
• W2288363860 cites W2083108329 @default.
• W2288363860 cites W2084054222 @default.
• W2288363860 cites W2085444186 @default.
• W2288363860 cites W2090045765 @default.
• W2288363860 cites W2090633127 @default.
• W2288363860 cites W2090770542 @default.
• W2288363860 cites W2098442982 @default.
• W2288363860 cites W2099716066 @default.
• W2288363860 cites W2103112566 @default.
• W2288363860 cites W2104625630 @default.
• W2288363860 cites W2105227785 @default.
• W2288363860 cites W2106047180 @default.
• W2288363860 cites W2112934435 @default.
• W2288363860 cites W2120816267 @default.
• W2288363860 cites W2131801978 @default.
• W2288363860 cites W2135903283 @default.
• W2288363860 cites W2141590023 @default.
• W2288363860 cites W2143663690 @default.
• W2288363860 cites W2150917623 @default.
• W2288363860 cites W2156423456 @default.
• W2288363860 cites W2334301670 @default.
• W2288363860 cites W4242123597 @default.
• W2288363860 doi "https://doi.org/10.1038/srep20523" @default.
• W2288363860 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4742808" @default.
• W2288363860 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26846452" @default.
• W2288363860 hasPublicationYear "2016" @default.
• W2288363860 type Work @default.
• W2288363860 sameAs 2288363860 @default.
• W2288363860 citedByCount "22" @default.
• W2288363860 countsByYear W22883638602017 @default.
• W2288363860 countsByYear W22883638602018 @default.
• W2288363860 countsByYear W22883638602019 @default.
• W2288363860 countsByYear W22883638602020 @default.
• W2288363860 countsByYear W22883638602021 @default.
• W2288363860 countsByYear W22883638602022 @default.
• W2288363860 crossrefType "journal-article" @default.
• W2288363860 hasAuthorship W2288363860A5004223061 @default.
• W2288363860 hasAuthorship W2288363860A5006445023 @default.
• W2288363860 hasAuthorship W2288363860A5011420293 @default.
• W2288363860 hasAuthorship W2288363860A5026374518 @default.
• W2288363860 hasAuthorship W2288363860A5033824240 @default.
• W2288363860 hasAuthorship W2288363860A5057019119 @default.
• W2288363860 hasAuthorship W2288363860A5057058881 @default.
• W2288363860 hasAuthorship W2288363860A5065392518 @default.
• W2288363860 hasAuthorship W2288363860A5082367364 @default.
• W2288363860 hasAuthorship W2288363860A5082856054 @default.
• W2288363860 hasAuthorship W2288363860A5084498555 @default.
• W2288363860 hasAuthorship W2288363860A5089298188 @default.

• next