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• W2288688086 abstract "Nine new cedrelone-type limonoid derivatives, walsunoids A-I (1-9), and 11 known compounds were isolated from the leaves of Walsura robusta. Walsunoid A (1) is a new degradation product of cedrelone-type limonoids, and walsunoid I (9) is a rare cedrelone-type limonoid amide. Their structures and absolute configurations were determined by spectroscopic data, single-crystal X-ray diffraction, and ECD data analyses. Five compounds showed moderate inhibitory activities against human and/or mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with IC50 values ranging from 0.69 to 9.9 μM." @default.
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• W2288688086 date "2016-03-03" @default.
• W2288688086 modified "2023-10-14" @default.
• W2288688086 title "Limonoids and Triterpenoids as 11β-HSD1 Inhibitors from <i>Walsura robusta</i>" @default.
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• W2288688086 doi "https://doi.org/10.1021/acs.jnatprod.5b00952" @default.
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