Matches in SemOpenAlex for { <https://semopenalex.org/work/W2288835804> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2288835804 abstract "Male Sprague-Dawley rats were exposed to increasing concentrations of ozone as follows: 0.12, 0.24, 0.36, 0.6, or 0.8 ppm. Controls were kept in chambers ventilated with filtered air. One-half of the animals in ozone was exposed for 12 h a day during daytime hours, and the other one-half of the animals was exposed for 12 h during nighttime. Cumulative labeling indexes were measured after 4 and 7 days in the terminal bronchioles, large intrapulmonary airways, trachea, and nasal epithelia. The penetration of the lesions from the bronchiole-alveolar junction into the alveolar zone was measured with quantitative morphometry. After 4 days of exposure, the extent of injury was dose dependent. Labeling indexes in the terminal bronchioles were 15-20% higher in animals exposed during nighttime compared with the animals exposed during daylight hours. On the other hand, depth of penetration of ozone lesions into the centriacinar region was not significantly different in animals exposed during the night compared with animals exposed during daytime. Labeling indexes in the large airways, trachea, or nasal cavity were not influenced by time of exposure. Between days 4 and 7, the lesions in the terminal bronchioles progressed only to a minimal degree (10%). It was concluded that the pattern of centriacinar tissue remodeling 1) followed a gradient based on ozone concentration and 2) was essentially complete after only 4 days of ozone exposure. Although a difference between daytime and nighttime exposure was observed, it was not considered to be large enough to invalidate conclusions drawn from studies in which animals are exposed to ozone during daylight hours." @default.
- W2288835804 created "2016-06-24" @default.
- W2288835804 creator A5027437494 @default.
- W2288835804 creator A5052451565 @default.
- W2288835804 creator A5065322216 @default.
- W2288835804 date "1997-06-01" @default.
- W2288835804 modified "2023-09-26" @default.
- W2288835804 title "Pulmonary cell kinetics and morphometry after ozone exposure: day versus night and dose response in rats" @default.
- W2288835804 doi "https://doi.org/10.1152/ajplung.1997.272.6.l1152" @default.
- W2288835804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9227517" @default.
- W2288835804 hasPublicationYear "1997" @default.
- W2288835804 type Work @default.
- W2288835804 sameAs 2288835804 @default.
- W2288835804 citedByCount "5" @default.
- W2288835804 countsByYear W22888358042016 @default.
- W2288835804 countsByYear W22888358042019 @default.
- W2288835804 crossrefType "journal-article" @default.
- W2288835804 hasAuthorship W2288835804A5027437494 @default.
- W2288835804 hasAuthorship W2288835804A5052451565 @default.
- W2288835804 hasAuthorship W2288835804A5065322216 @default.
- W2288835804 hasConcept C126322002 @default.
- W2288835804 hasConcept C127413603 @default.
- W2288835804 hasConcept C140793950 @default.
- W2288835804 hasConcept C178790620 @default.
- W2288835804 hasConcept C185592680 @default.
- W2288835804 hasConcept C2777714996 @default.
- W2288835804 hasConcept C2780957178 @default.
- W2288835804 hasConcept C42475967 @default.
- W2288835804 hasConcept C508106653 @default.
- W2288835804 hasConcept C71924100 @default.
- W2288835804 hasConcept C80107235 @default.
- W2288835804 hasConcept C86803240 @default.
- W2288835804 hasConceptScore W2288835804C126322002 @default.
- W2288835804 hasConceptScore W2288835804C127413603 @default.
- W2288835804 hasConceptScore W2288835804C140793950 @default.
- W2288835804 hasConceptScore W2288835804C178790620 @default.
- W2288835804 hasConceptScore W2288835804C185592680 @default.
- W2288835804 hasConceptScore W2288835804C2777714996 @default.
- W2288835804 hasConceptScore W2288835804C2780957178 @default.
- W2288835804 hasConceptScore W2288835804C42475967 @default.
- W2288835804 hasConceptScore W2288835804C508106653 @default.
- W2288835804 hasConceptScore W2288835804C71924100 @default.
- W2288835804 hasConceptScore W2288835804C80107235 @default.
- W2288835804 hasConceptScore W2288835804C86803240 @default.
- W2288835804 hasLocation W22888358041 @default.
- W2288835804 hasLocation W22888358042 @default.
- W2288835804 hasOpenAccess W2288835804 @default.
- W2288835804 hasPrimaryLocation W22888358041 @default.
- W2288835804 hasRelatedWork W1501916255 @default.
- W2288835804 hasRelatedWork W1971192871 @default.
- W2288835804 hasRelatedWork W2018191952 @default.
- W2288835804 hasRelatedWork W2101891671 @default.
- W2288835804 hasRelatedWork W2317814092 @default.
- W2288835804 hasRelatedWork W2367249834 @default.
- W2288835804 hasRelatedWork W2950191853 @default.
- W2288835804 hasRelatedWork W2951519276 @default.
- W2288835804 hasRelatedWork W2951633014 @default.
- W2288835804 hasRelatedWork W2953284829 @default.
- W2288835804 isParatext "false" @default.
- W2288835804 isRetracted "false" @default.
- W2288835804 magId "2288835804" @default.
- W2288835804 workType "article" @default.