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- W2288863688 abstract "Menstrual irregularities are believed to often follow the tubectomy operation, possibly because the ovarian blood supply is altered and horm onal imbalance results. This study was designed to determine, with the help of hormonal colpocytology and endometrial histology, whether hormon al imbalance occurs after tubectomy. Subjects were 100 women attending the tubectomy follow-up clinic. All had been tubectomized 2 or more years earlier. On the 5th and 6th days of their menstrual cycles, a group was treated with an antibiotic vaginal pessary consisting of .25 gm of Chloramphenicol. From the 8th to the 24th day, serial vaginal sme ars were taken. The maturation index (MI), maturation value (MV), and k aryopyknotic index (KI) were evaluated. Endometrial biopsies were taken on Day 24 of the menstrual cycles. Of the 100 women, 98 had ovulatroy c ycles as shown by endometrial biopsy. The 2 having anovulatory cycles w ere in the treated group. Their MVs and KIs were low. None showed evid ence of hyperestrogenism either in their colpocytogram or endometrial hi stology. Disturbed ovarian function was not shown. Prior anitbiotic tr eatment is essential for hormonal cytology, as in the majority of untrea ted women the presence of Doderlein bacilli, debris, and leukocytes in the follicular phase renders preparations unsatisfactory for hormonal ev aluation. Chloramphenicol has no direct effect on the vaginal epitheliu m but tetracyclines cause massive desquamation." @default.
- W2288863688 created "2016-06-24" @default.
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- W2288863688 date "1975-07-01" @default.
- W2288863688 modified "2023-09-23" @default.
- W2288863688 title "Study correlating endometrial biopsies and vaginal cytology in one hundred tubectomized women." @default.
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