FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2289069921> ?p ?o ?g. }

• W2289069921 endingPage "E247" @default.
• W2289069921 startingPage "E238" @default.
• W2289069921 abstract "Among potential contributors for the increased incidence of metabolic diseases is the developmental exposure to endocrine-disrupting chemicals such as bisphenol A (BPA). BPA is an estrogenic chemical used in a variety of consumer products. Evidence points to interactions of BPA with the prevailing environment. The aim of this study was to assess the effects of prenatal exposure to BPA on postnatal metabolic outcomes, including insulin resistance, adipose tissue distribution, adipocyte morphometry, and expression of inflammatory markers in adipose tissue as well as to assess whether postnatal overfeeding would exacerbate these effects. Findings indicate that prenatal BPA exposure leads to insulin resistance in adulthood in the first breeder cohort ( study 1), but not in the second cohort ( study 2), which is suggestive of potential differences in genetic susceptibility. BPA exposure induced adipocyte hypertrophy in the visceral fat depot without an accompanying increase in visceral fat mass or increased CD68, a marker of macrophage infiltration, in the subcutaneous fat depot. Cohens effect size analysis found the ratio of visceral to subcutanous fat depot in the prenatal BPA-treated overfed group to be higher compared with the control-overfed group. Altogether, these results suggest that exposure to BPA during fetal life at levels found in humans can program metabolic outcomes that lead to insulin resistance, a forerunner of type 2 diabetes, with postnatal obesity failing to manifest any interaction with prenatal BPA relative to insulin resistance and adipocyte hypertrophy." @default.
• W2289069921 created "2016-06-24" @default.
• W2289069921 creator A5023564064 @default.
• W2289069921 creator A5024258221 @default.
• W2289069921 creator A5029119143 @default.
• W2289069921 creator A5045520767 @default.
• W2289069921 creator A5049027825 @default.
• W2289069921 creator A5052065231 @default.
• W2289069921 creator A5063679531 @default.
• W2289069921 creator A5090454827 @default.
• W2289069921 date "2016-02-01" @default.
• W2289069921 modified "2023-10-18" @default.
• W2289069921 title "Developmental programming: interaction between prenatal BPA exposure and postnatal adiposity on metabolic variables in female sheep" @default.
• W2289069921 cites W1965506605 @default.
• W2289069921 cites W1966515286 @default.
• W2289069921 cites W1970760886 @default.
• W2289069921 cites W1974313427 @default.
• W2289069921 cites W1974435147 @default.
• W2289069921 cites W1975752932 @default.
• W2289069921 cites W1978240533 @default.
• W2289069921 cites W1983953582 @default.
• W2289069921 cites W1984254033 @default.
• W2289069921 cites W1992386938 @default.
• W2289069921 cites W2000281137 @default.
• W2289069921 cites W2001054657 @default.
• W2289069921 cites W2007570393 @default.
• W2289069921 cites W2007586461 @default.
• W2289069921 cites W2010983232 @default.
• W2289069921 cites W2016587830 @default.
• W2289069921 cites W2020338693 @default.
• W2289069921 cites W2024201289 @default.
• W2289069921 cites W2032900856 @default.
• W2289069921 cites W2036139926 @default.
• W2289069921 cites W2038125044 @default.
• W2289069921 cites W2041717284 @default.
• W2289069921 cites W2044104475 @default.
• W2289069921 cites W2044346508 @default.
• W2289069921 cites W2046176216 @default.
• W2289069921 cites W2050776663 @default.
• W2289069921 cites W2055757491 @default.
• W2289069921 cites W2056645812 @default.
• W2289069921 cites W2066304268 @default.
• W2289069921 cites W2067753015 @default.
• W2289069921 cites W2068565367 @default.
• W2289069921 cites W2068630231 @default.
• W2289069921 cites W2074854055 @default.
• W2289069921 cites W2079670970 @default.
• W2289069921 cites W2082835899 @default.
• W2289069921 cites W2089427889 @default.
• W2289069921 cites W2091262245 @default.
• W2289069921 cites W2092890006 @default.
• W2289069921 cites W2094433930 @default.
• W2289069921 cites W2100361552 @default.
• W2289069921 cites W2107832644 @default.
• W2289069921 cites W2110824386 @default.
• W2289069921 cites W2119057367 @default.
• W2289069921 cites W2127187614 @default.
• W2289069921 cites W2140661981 @default.
• W2289069921 cites W2144313139 @default.
• W2289069921 cites W2144587386 @default.
• W2289069921 cites W2147722922 @default.
• W2289069921 cites W2149861144 @default.
• W2289069921 cites W2149930945 @default.
• W2289069921 cites W2158418727 @default.
• W2289069921 cites W2165644935 @default.
• W2289069921 cites W2172193326 @default.
• W2289069921 cites W2470404765 @default.
• W2289069921 cites W2610204288 @default.
• W2289069921 doi "https://doi.org/10.1152/ajpendo.00425.2015" @default.
• W2289069921 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4888526" @default.
• W2289069921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26646100" @default.
• W2289069921 hasPublicationYear "2016" @default.
• W2289069921 type Work @default.
• W2289069921 sameAs 2289069921 @default.
• W2289069921 citedByCount "43" @default.
• W2289069921 countsByYear W22890699212016 @default.
• W2289069921 countsByYear W22890699212017 @default.
• W2289069921 countsByYear W22890699212018 @default.
• W2289069921 countsByYear W22890699212019 @default.
• W2289069921 countsByYear W22890699212020 @default.
• W2289069921 countsByYear W22890699212021 @default.
• W2289069921 countsByYear W22890699212022 @default.
• W2289069921 countsByYear W22890699212023 @default.
• W2289069921 crossrefType "journal-article" @default.
• W2289069921 hasAuthorship W2289069921A5023564064 @default.
• W2289069921 hasAuthorship W2289069921A5024258221 @default.
• W2289069921 hasAuthorship W2289069921A5029119143 @default.
• W2289069921 hasAuthorship W2289069921A5045520767 @default.
• W2289069921 hasAuthorship W2289069921A5049027825 @default.
• W2289069921 hasAuthorship W2289069921A5052065231 @default.
• W2289069921 hasAuthorship W2289069921A5063679531 @default.
• W2289069921 hasAuthorship W2289069921A5090454827 @default.
• W2289069921 hasBestOaLocation W22890699211 @default.
• W2289069921 hasConcept C126322002 @default.
• W2289069921 hasConcept C134018914 @default.
• W2289069921 hasConcept C171089720 @default.
• W2289069921 hasConcept C2776175234 @default.
• W2289069921 hasConcept C2777391703 @default.

• next