Matches in SemOpenAlex for { <https://semopenalex.org/work/W2289219011> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2289219011 endingPage "172" @default.
- W2289219011 startingPage "169" @default.
- W2289219011 abstract "The effect upon the survival of skin flaps of several drugs which affect the adrenergic system was studied in rats. In control animals 41% of the skin flaps had survived seven days after the operation. Reserpine (1 mg/kg) injected intraperioneally (i.p.) three days and one day before the flap operation increased the surviving flap area by 75% (p<0.001) as compared to control rats injected with saline. I.p. injection of guanethidine (5 mg/kg) or bretylium (10 mg/kg) every 12 hours, starting 24 hours before surgery and continued for 5 consecutive days, also increased the surviving flap area (19 and 33% respectively p<0.001). The surviving flap area was unchanged when desipramine (5 mg/kg) was injected in the same way and was decreased by 15% (p<0.05) following i.p. injection of the MAO inhibitor pheniprazine (5 mg/kg). Treatment with α-methyl-p-tyrosine (75 mg/kg), i.p. 30 min before surgery or 6-hydroxydopamine (50 mg/kg) i.v. 24 hours prior to surgery also increased the flap survival (56 and 49% increase in surviving flap area, respectively, p<0.001). The results demonstrated that the survival of skin flaps increased when the function of the adrenergic nervous system was inhibited. Enhanced sympathetic nervous activity slightly reduced or did not affect skin flap survival." @default.
- W2289219011 created "2016-06-24" @default.
- W2289219011 creator A5001461726 @default.
- W2289219011 creator A5026826778 @default.
- W2289219011 date "1976-01-01" @default.
- W2289219011 modified "2023-09-30" @default.
- W2289219011 title "Increased Survival of Experimental Skin Flaps in Rats Following Treatment with Antiadrenergic Drugs" @default.
- W2289219011 cites W1963841298 @default.
- W2289219011 cites W1974461258 @default.
- W2289219011 cites W1980784555 @default.
- W2289219011 cites W1982869661 @default.
- W2289219011 cites W1997587411 @default.
- W2289219011 cites W2019625812 @default.
- W2289219011 cites W2020971661 @default.
- W2289219011 cites W2026557710 @default.
- W2289219011 cites W2047054609 @default.
- W2289219011 cites W2055375196 @default.
- W2289219011 cites W2064111074 @default.
- W2289219011 cites W2070293738 @default.
- W2289219011 cites W2090639112 @default.
- W2289219011 cites W2090808239 @default.
- W2289219011 cites W2132291912 @default.
- W2289219011 cites W2139205597 @default.
- W2289219011 doi "https://doi.org/10.3109/02844317609012964" @default.
- W2289219011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/95655" @default.
- W2289219011 hasPublicationYear "1976" @default.
- W2289219011 type Work @default.
- W2289219011 sameAs 2289219011 @default.
- W2289219011 citedByCount "49" @default.
- W2289219011 countsByYear W22892190112012 @default.
- W2289219011 countsByYear W22892190112015 @default.
- W2289219011 countsByYear W22892190112019 @default.
- W2289219011 countsByYear W22892190112022 @default.
- W2289219011 crossrefType "journal-article" @default.
- W2289219011 hasAuthorship W2289219011A5001461726 @default.
- W2289219011 hasAuthorship W2289219011A5026826778 @default.
- W2289219011 hasConcept C126322002 @default.
- W2289219011 hasConcept C141071460 @default.
- W2289219011 hasConcept C158453852 @default.
- W2289219011 hasConcept C170493617 @default.
- W2289219011 hasConcept C24998067 @default.
- W2289219011 hasConcept C2776232365 @default.
- W2289219011 hasConcept C2777397205 @default.
- W2289219011 hasConcept C2777842393 @default.
- W2289219011 hasConcept C2779117456 @default.
- W2289219011 hasConcept C2779177272 @default.
- W2289219011 hasConcept C2779190097 @default.
- W2289219011 hasConcept C2780250439 @default.
- W2289219011 hasConcept C2781161787 @default.
- W2289219011 hasConcept C42219234 @default.
- W2289219011 hasConcept C71924100 @default.
- W2289219011 hasConceptScore W2289219011C126322002 @default.
- W2289219011 hasConceptScore W2289219011C141071460 @default.
- W2289219011 hasConceptScore W2289219011C158453852 @default.
- W2289219011 hasConceptScore W2289219011C170493617 @default.
- W2289219011 hasConceptScore W2289219011C24998067 @default.
- W2289219011 hasConceptScore W2289219011C2776232365 @default.
- W2289219011 hasConceptScore W2289219011C2777397205 @default.
- W2289219011 hasConceptScore W2289219011C2777842393 @default.
- W2289219011 hasConceptScore W2289219011C2779117456 @default.
- W2289219011 hasConceptScore W2289219011C2779177272 @default.
- W2289219011 hasConceptScore W2289219011C2779190097 @default.
- W2289219011 hasConceptScore W2289219011C2780250439 @default.
- W2289219011 hasConceptScore W2289219011C2781161787 @default.
- W2289219011 hasConceptScore W2289219011C42219234 @default.
- W2289219011 hasConceptScore W2289219011C71924100 @default.
- W2289219011 hasIssue "3" @default.
- W2289219011 hasLocation W22892190111 @default.
- W2289219011 hasLocation W22892190112 @default.
- W2289219011 hasOpenAccess W2289219011 @default.
- W2289219011 hasPrimaryLocation W22892190111 @default.
- W2289219011 hasRelatedWork W1963904084 @default.
- W2289219011 hasRelatedWork W1984057810 @default.
- W2289219011 hasRelatedWork W2022622207 @default.
- W2289219011 hasRelatedWork W2026557710 @default.
- W2289219011 hasRelatedWork W2036038529 @default.
- W2289219011 hasRelatedWork W2094106806 @default.
- W2289219011 hasRelatedWork W2143946529 @default.
- W2289219011 hasRelatedWork W2244730631 @default.
- W2289219011 hasRelatedWork W2278625675 @default.
- W2289219011 hasRelatedWork W2289219011 @default.
- W2289219011 hasVolume "10" @default.
- W2289219011 isParatext "false" @default.
- W2289219011 isRetracted "false" @default.
- W2289219011 magId "2289219011" @default.
- W2289219011 workType "article" @default.