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- W2289367243 abstract "Although copper (Cu) is recognized as an essential trace element, uncertainties remain regarding Cu reference values for humans, as illustrated by discrepancies between recommendations issued by different national authorities. This review examines human studies published since 1990 on relationships between Cu intake, Cu balance, biomarkers of Cu status, and health. It points out several gaps and unresolved issues which make it difficult to assess Cu requirements. Results from balance studies suggest that daily intakes below 0.8 mg/day lead to net Cu losses, while net gains are consistently observed above 2.4 mg/day. However, because of an incomplete collection of losses in all studies, a precise estimation of Cu requirements cannot be derived from available data. Data regarding the relationship between Cu intake and potential biomarkers are either too preliminary or inconclusive because of low specificity or low sensitivity to change in dietary Cu over a wide range of intakes. Results from observation and intervention studies do not support a link between Cu and a risk of cardiovascular disease, cognitive decline, arthritis or cancer for intakes ranging from 0.6 to 3 mg/day, and limited evidence exists for impaired immune function in healthy subjects with a very low (0.38 mg/day) Cu intake. However, data from observation studies should be regarded with caution because of uncertainties regarding Cu concentration in various foods and water. Further studies that accurately evaluate Cu exposure based on reliable biomarkers of Cu status are needed." @default.
- W2289367243 created "2016-06-24" @default.
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- W2289367243 date "2016-05-01" @default.
- W2289367243 modified "2023-10-16" @default.
- W2289367243 title "Dietary copper and human health: Current evidence and unresolved issues" @default.
- W2289367243 cites W1826455295 @default.
- W2289367243 cites W1881597431 @default.
- W2289367243 cites W1930476736 @default.
- W2289367243 cites W1932317174 @default.
- W2289367243 cites W1934678104 @default.
- W2289367243 cites W1950336144 @default.
- W2289367243 cites W1964254856 @default.
- W2289367243 cites W1966736088 @default.
- W2289367243 cites W1969712583 @default.
- W2289367243 cites W1978424761 @default.
- W2289367243 cites W1980209371 @default.
- W2289367243 cites W1984774950 @default.
- W2289367243 cites W1986786483 @default.
- W2289367243 cites W1993058514 @default.
- W2289367243 cites W1995570043 @default.
- W2289367243 cites W2009238532 @default.
- W2289367243 cites W2012094986 @default.
- W2289367243 cites W2015391535 @default.
- W2289367243 cites W2021317348 @default.
- W2289367243 cites W2029334799 @default.
- W2289367243 cites W2031033178 @default.
- W2289367243 cites W2031039033 @default.
- W2289367243 cites W2038623955 @default.
- W2289367243 cites W2049801032 @default.
- W2289367243 cites W2051863096 @default.
- W2289367243 cites W2056784592 @default.
- W2289367243 cites W2056986552 @default.
- W2289367243 cites W2063313240 @default.
- W2289367243 cites W2066095350 @default.
- W2289367243 cites W2066916731 @default.
- W2289367243 cites W2072929439 @default.
- W2289367243 cites W2073534753 @default.
- W2289367243 cites W2077444509 @default.
- W2289367243 cites W2083887224 @default.
- W2289367243 cites W2084986283 @default.
- W2289367243 cites W2085536739 @default.
- W2289367243 cites W2087708629 @default.
- W2289367243 cites W2094601838 @default.
- W2289367243 cites W2096833197 @default.
- W2289367243 cites W2097417532 @default.
- W2289367243 cites W2099464259 @default.
- W2289367243 cites W2099739975 @default.
- W2289367243 cites W2104281953 @default.
- W2289367243 cites W2106230607 @default.
- W2289367243 cites W2106927547 @default.
- W2289367243 cites W2107418498 @default.
- W2289367243 cites W2108552230 @default.
- W2289367243 cites W2109349820 @default.
- W2289367243 cites W2113146190 @default.
- W2289367243 cites W2114017986 @default.
- W2289367243 cites W2118865702 @default.
- W2289367243 cites W2124103287 @default.
- W2289367243 cites W2125365706 @default.
- W2289367243 cites W2127144499 @default.
- W2289367243 cites W2129295451 @default.
- W2289367243 cites W2131872734 @default.
- W2289367243 cites W2133461561 @default.
- W2289367243 cites W2139792780 @default.
- W2289367243 cites W2142719229 @default.
- W2289367243 cites W2145821936 @default.
- W2289367243 cites W2145844296 @default.
- W2289367243 cites W2147806246 @default.
- W2289367243 cites W2150867276 @default.
- W2289367243 cites W2158445858 @default.
- W2289367243 cites W2159704368 @default.
- W2289367243 cites W2159711642 @default.
- W2289367243 cites W2159911605 @default.
- W2289367243 cites W2161136053 @default.
- W2289367243 cites W2163591814 @default.
- W2289367243 cites W2169135174 @default.
- W2289367243 cites W2172208206 @default.
- W2289367243 cites W2247851187 @default.
- W2289367243 cites W4229882081 @default.
- W2289367243 cites W4239823765 @default.
- W2289367243 cites W4241707225 @default.
- W2289367243 cites W4249358706 @default.
- W2289367243 cites W4250363211 @default.
- W2289367243 cites W4297573539 @default.
- W2289367243 doi "https://doi.org/10.1016/j.jtemb.2016.02.006" @default.
- W2289367243 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27049134" @default.
- W2289367243 hasPublicationYear "2016" @default.
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