FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2289368082> ?p ?o ?g. }

• W2289368082 endingPage "90" @default.
• W2289368082 startingPage "83" @default.
• W2289368082 abstract "Antimuscarinic medications are used to treat nonneurogenic overactive bladder refractory to nonpharmacologic therapy. Side effects such as dry mouth, constipation, blurred vision, dizziness, and impaired cognition limit the tolerability of therapy and are largely responsible for high discontinuation rates. Oxybutynin is a potent muscarinic receptor antagonist whose primary metabolite after first-pass hepatic metabolism is considered largely responsible for its associated anticholinergic side effects. Transdermal administration of medications bypasses hepatic processing. Specifically with oxybutynin, whose low molecular weight permits transdermal administration, bioavailability of the parent drug with oral administration is less than 10%, whereas with transdermal delivery is a minimum of 80%. The result has been an improved side effect profile in multiple clinical trials with maintained efficacy relative to placebo; however, the drug may still be discontinued by patients due to anticholinergic side effects and application site reactions. Transdermal oxybutynin is available as a patch that is changed every 3-4 days, a gel available in individual sachets, or via a metered-dose pump that is applied daily. The transdermal patch was briefly available as an over-the-counter medication for adult women, although at this time all transdermal formulations are available by prescription only." @default.
• W2289368082 created "2016-06-24" @default.
• W2289368082 creator A5026428516 @default.
• W2289368082 creator A5042646128 @default.
• W2289368082 creator A5044996298 @default.
• W2289368082 creator A5054323383 @default.
• W2289368082 creator A5069057391 @default.
• W2289368082 creator A5084679639 @default.
• W2289368082 date "2016-01-19" @default.
• W2289368082 modified "2023-10-10" @default.
• W2289368082 title "An update on the use of transdermal oxybutynin in the management of overactive bladder disorder" @default.
• W2289368082 cites W1233787658 @default.
• W2289368082 cites W1496249181 @default.
• W2289368082 cites W1526318214 @default.
• W2289368082 cites W1541452549 @default.
• W2289368082 cites W1567826565 @default.
• W2289368082 cites W1586583724 @default.
• W2289368082 cites W1596244567 @default.
• W2289368082 cites W1888832531 @default.
• W2289368082 cites W1928285801 @default.
• W2289368082 cites W1973321971 @default.
• W2289368082 cites W1978083855 @default.
• W2289368082 cites W1989372559 @default.
• W2289368082 cites W1990105343 @default.
• W2289368082 cites W1994653403 @default.
• W2289368082 cites W2001275235 @default.
• W2289368082 cites W2012897345 @default.
• W2289368082 cites W2014556601 @default.
• W2289368082 cites W2016181184 @default.
• W2289368082 cites W2040008446 @default.
• W2289368082 cites W2044943786 @default.
• W2289368082 cites W2054271813 @default.
• W2289368082 cites W2057535748 @default.
• W2289368082 cites W2057756573 @default.
• W2289368082 cites W2058955332 @default.
• W2289368082 cites W2064430566 @default.
• W2289368082 cites W2068451975 @default.
• W2289368082 cites W2071052332 @default.
• W2289368082 cites W2073754334 @default.
• W2289368082 cites W2097487242 @default.
• W2289368082 cites W2098709306 @default.
• W2289368082 cites W2102524054 @default.
• W2289368082 cites W2122751872 @default.
• W2289368082 cites W2150043453 @default.
• W2289368082 cites W2151930795 @default.
• W2289368082 cites W2153218780 @default.
• W2289368082 cites W2160396622 @default.
• W2289368082 cites W2169382589 @default.
• W2289368082 cites W2169527010 @default.
• W2289368082 cites W2272230431 @default.
• W2289368082 cites W2299994708 @default.
• W2289368082 cites W2327680783 @default.
• W2289368082 cites W2405474128 @default.
• W2289368082 cites W2418036755 @default.
• W2289368082 cites W4302919807 @default.
• W2289368082 cites W95531539 @default.
• W2289368082 doi "https://doi.org/10.1177/1756287215626312" @default.
• W2289368082 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4772360" @default.
• W2289368082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27034721" @default.
• W2289368082 hasPublicationYear "2016" @default.
• W2289368082 type Work @default.
• W2289368082 sameAs 2289368082 @default.
• W2289368082 citedByCount "14" @default.
• W2289368082 countsByYear W22893680822016 @default.
• W2289368082 countsByYear W22893680822017 @default.
• W2289368082 countsByYear W22893680822018 @default.
• W2289368082 countsByYear W22893680822020 @default.
• W2289368082 countsByYear W22893680822021 @default.
• W2289368082 countsByYear W22893680822023 @default.
• W2289368082 crossrefType "journal-article" @default.
• W2289368082 hasAuthorship W2289368082A5026428516 @default.
• W2289368082 hasAuthorship W2289368082A5042646128 @default.
• W2289368082 hasAuthorship W2289368082A5044996298 @default.
• W2289368082 hasAuthorship W2289368082A5054323383 @default.
• W2289368082 hasAuthorship W2289368082A5069057391 @default.
• W2289368082 hasAuthorship W2289368082A5084679639 @default.
• W2289368082 hasBestOaLocation W22893680821 @default.
• W2289368082 hasConcept C126322002 @default.
• W2289368082 hasConcept C142724271 @default.
• W2289368082 hasConcept C197934379 @default.
• W2289368082 hasConcept C204787440 @default.
• W2289368082 hasConcept C205679159 @default.
• W2289368082 hasConcept C2775842315 @default.
• W2289368082 hasConcept C2777844464 @default.
• W2289368082 hasConcept C2778375690 @default.
• W2289368082 hasConcept C2778689640 @default.
• W2289368082 hasConcept C2778715236 @default.
• W2289368082 hasConcept C2778941218 @default.
• W2289368082 hasConcept C42219234 @default.
• W2289368082 hasConcept C71924100 @default.
• W2289368082 hasConcept C98274493 @default.
• W2289368082 hasConceptScore W2289368082C126322002 @default.
• W2289368082 hasConceptScore W2289368082C142724271 @default.
• W2289368082 hasConceptScore W2289368082C197934379 @default.
• W2289368082 hasConceptScore W2289368082C204787440 @default.
• W2289368082 hasConceptScore W2289368082C205679159 @default.
• W2289368082 hasConceptScore W2289368082C2775842315 @default.
• W2289368082 hasConceptScore W2289368082C2777844464 @default.

• next