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- W2289419105 abstract "Helicobacter pylori CagA protein, the cagA gen product, has been considered as a virulence factor associated with a considerable increase risk for develops severe gastric illness. The purpose of this research was to design a molecular and bioinformatics strategy that allowed the establishment of phosphorylation status of the tyrosine residue of the CagA protein. The amplifi cation and sequencing of the variable fragment region of cagA in the positive CagA samples were used to do the bioinformatics analysis in order to establish the characteristics of the EPIYA motifs. The presence of the EPIYA-A and EPIYA-B motifs, followed by one or two EPIYA-C repetitions, similar to those reported previously for occidental countries were set up. From the diffe- rent bioinformatics applications that were employed only one group of tools proved to be useful to characterize the repeated units presents in the CagA protein." @default.
- W2289419105 created "2016-06-24" @default.
- W2289419105 creator A5059188897 @default.
- W2289419105 date "2009-01-01" @default.
- W2289419105 modified "2023-09-27" @default.
- W2289419105 title "Caracterización molecular y bioinformática de la proteína CagA de Helicobacter pylori a partir de biopsias gástricas de pacientes colombianos Molecular and bioinformatic characterization of Helicobacter pylori CagA protein using gastric biopsies of Colombian patients" @default.
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