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- W2289706072 abstract "Background And Objectives: Diabetic ketoacidosis is one of the most common endocrinal emergency in the world. Electrolyte and fluid imbalances are known to occur in diabetic ketoacidosis. Phosphorus containing compounds have important roles in cell structure, function and acid base balance. Phosphorus depletion occurs in diabetic ketoacidosis owing trans-cellular shift and hyperphosphaturia. This study was undertaken to study phosphorus levels and its correlation to clinical profile in patients with diabetic ketoacidosis. Methods: An prospective observational study is undertaken in 110 diabetic ketoacidosis patients at tertiary care centre. Serum phosphorus levels are performed at baseline, on day 1and on day 3.Ocurrence of complications of hypophosphatemia and hyperphosphatemia, outcome measures including length of hospital stay and mortality were assessed. in 48% patients on day 1. Among symptomatic hypophosphotemics , respiratory distress was the most common symptom. The mean length of stay among hypophosphatemics (10 days) was significantly higher than euphosphatemics or hyperphosphatemics (5.45 days).There was statistically significant negative correlation between HBA1C levels and serum phosphorus levels at baseline. Mortality rate was found high in hypophosphatemic group however this observation was found to be statistically insignificant. Interpretation And Conclusion: This study demonstrated that phosphorus the neglected aspect of diabetic ketoacidosis needs due consideration. All patients having symptomatic hypophosphatemia in the form of unexplained respiratory distress and difficulty in weaning off from ventilator need appropriate attention for" @default.
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- W2289706072 date "2015-05-21" @default.
- W2289706072 modified "2023-09-27" @default.
- W2289706072 title "Study of Serum Phosphorus Levels and Its Correlation with Clinical Profile in Patients with Diabetic Ketoacidosis" @default.
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- W2289706072 doi "https://doi.org/10.6084/m9.figshare.1421934.v1" @default.
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