Matches in SemOpenAlex for { <https://semopenalex.org/work/W2289738337> ?p ?o ?g. }
- W2289738337 endingPage "e0004530" @default.
- W2289738337 startingPage "e0004530" @default.
- W2289738337 abstract "Introduction Reports of high rates of primary microcephaly and Guillain–Barré syndrome associated with Zika virus infection in French Polynesia and Brazil have raised concerns that the virus circulating in these regions is a rapidly developing neuropathic, teratogenic, emerging infectious public health threat. There are no licensed medical countermeasures (vaccines, therapies or preventive drugs) available for Zika virus infection and disease. The Pan American Health Organization (PAHO) predicts that Zika virus will continue to spread and eventually reach all countries and territories in the Americas with endemic Aedes mosquitoes. This paper reviews the status of the Zika virus outbreak, including medical countermeasure options, with a focus on how the epidemiology, insect vectors, neuropathology, virology and immunology inform options and strategies available for medical countermeasure development and deployment. Methods Multiple information sources were employed to support the review. These included publically available literature, patents, official communications, English and Lusophone lay press. Online surveys were distributed to physicians in the US, Mexico and Argentina and responses analyzed. Computational epitope analysis as well as infectious disease outbreak modeling and forecasting were implemented. Field observations in Brazil were compiled and interviews conducted with public health officials." @default.
- W2289738337 created "2016-06-24" @default.
- W2289738337 creator A5002693144 @default.
- W2289738337 creator A5015224335 @default.
- W2289738337 creator A5016366181 @default.
- W2289738337 creator A5022518932 @default.
- W2289738337 creator A5029728611 @default.
- W2289738337 creator A5032119933 @default.
- W2289738337 creator A5042879572 @default.
- W2289738337 creator A5052404676 @default.
- W2289738337 creator A5057586162 @default.
- W2289738337 creator A5059712524 @default.
- W2289738337 creator A5075764409 @default.
- W2289738337 creator A5088493407 @default.
- W2289738337 creator A5089336676 @default.
- W2289738337 date "2016-03-02" @default.
- W2289738337 modified "2023-10-03" @default.
- W2289738337 title "Zika Virus: Medical Countermeasure Development Challenges" @default.
- W2289738337 cites W1020548474 @default.
- W2289738337 cites W1558143285 @default.
- W2289738337 cites W1794962712 @default.
- W2289738337 cites W1857453373 @default.
- W2289738337 cites W1897094044 @default.
- W2289738337 cites W1952166052 @default.
- W2289738337 cites W1967826883 @default.
- W2289738337 cites W1971242419 @default.
- W2289738337 cites W1972549376 @default.
- W2289738337 cites W1973619678 @default.
- W2289738337 cites W1975120587 @default.
- W2289738337 cites W1979773004 @default.
- W2289738337 cites W1980376903 @default.
- W2289738337 cites W1980405204 @default.
- W2289738337 cites W1981093311 @default.
- W2289738337 cites W1981407198 @default.
- W2289738337 cites W1981688796 @default.
- W2289738337 cites W1982825669 @default.
- W2289738337 cites W1985648558 @default.
- W2289738337 cites W1992501110 @default.
- W2289738337 cites W2002998231 @default.
- W2289738337 cites W2003944513 @default.
- W2289738337 cites W2006146542 @default.
- W2289738337 cites W2010165373 @default.
- W2289738337 cites W2014546847 @default.
- W2289738337 cites W2018294138 @default.
- W2289738337 cites W2021821598 @default.
- W2289738337 cites W2023100352 @default.
- W2289738337 cites W2030178550 @default.
- W2289738337 cites W2036265216 @default.
- W2289738337 cites W2046998617 @default.
- W2289738337 cites W2047025337 @default.
- W2289738337 cites W2056690166 @default.
- W2289738337 cites W2060303925 @default.
- W2289738337 cites W2062504884 @default.
- W2289738337 cites W2063140977 @default.
- W2289738337 cites W2065311998 @default.
- W2289738337 cites W2080582088 @default.
- W2289738337 cites W2080642763 @default.
- W2289738337 cites W2085335543 @default.
- W2289738337 cites W2090127796 @default.
- W2289738337 cites W2093755621 @default.
- W2289738337 cites W2104024599 @default.
- W2289738337 cites W2105104428 @default.
- W2289738337 cites W2110122933 @default.
- W2289738337 cites W2117649585 @default.
- W2289738337 cites W2122349387 @default.
- W2289738337 cites W2125427423 @default.
- W2289738337 cites W2134898458 @default.
- W2289738337 cites W2141210267 @default.
- W2289738337 cites W2141954066 @default.
- W2289738337 cites W2144932456 @default.
- W2289738337 cites W2148538365 @default.
- W2289738337 cites W2150244847 @default.
- W2289738337 cites W2151551773 @default.
- W2289738337 cites W2151986531 @default.
- W2289738337 cites W2152546486 @default.
- W2289738337 cites W2156864709 @default.
- W2289738337 cites W2160023890 @default.
- W2289738337 cites W2170812841 @default.
- W2289738337 cites W2188334361 @default.
- W2289738337 cites W2224061626 @default.
- W2289738337 cites W2256093006 @default.
- W2289738337 cites W2266284658 @default.
- W2289738337 cites W2268567012 @default.
- W2289738337 cites W2285713692 @default.
- W2289738337 cites W2288668982 @default.
- W2289738337 cites W2290748042 @default.
- W2289738337 cites W2316635052 @default.
- W2289738337 cites W2332545245 @default.
- W2289738337 cites W2337074877 @default.
- W2289738337 cites W2405324653 @default.
- W2289738337 cites W2409707370 @default.
- W2289738337 cites W2413047276 @default.
- W2289738337 cites W2416226222 @default.
- W2289738337 cites W2469232091 @default.
- W2289738337 cites W2612252853 @default.
- W2289738337 doi "https://doi.org/10.1371/journal.pntd.0004530" @default.
- W2289738337 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4774925" @default.
- W2289738337 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26934531" @default.