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- W2289740840 abstract "Vitiligo is a common acquired pigmentary disorder affecting the skin of all ages and both sexes around the world. Presents as localised milky white patches of depigmentation which tend to progress in due course. It affects about 1% of the world population and the incidence is higher in India ranging from 3% to 8% approximately. There is psychological morbidity due to cosmetic disfigurement and no definite treatment is available. So there is a need to find better drug. The aim of our study is to compare the efficacy and safety of a new drug, Basic fibroblast growth factor {b FGF} 0.1% solution with the standard Betamethasone valerate (BV)0.1% ointment in patients with clinically diagnosed vitiligo. A prospective, comparative and interventional study was done on 62 patients with vitiligo patches, 31 in Group A were put on topical Basic fibroblast growth factor (b FGF) 0.1% solution and 31 in Group B on topical (BV) 0.1% ointment for 16 weeks. At the end of 1 st , 2 nd, ,3 rd and 4 th month the lesions were assessed for repigmentation, appearance of new lesions and adverse effects. After 16 weeks statistical analysis was done with Student T test. Patients in Group A showed more repigmentation in the patches than Group B patients. Topical (b FGF) was found to be more efficacious, safe and tolerable without any major side effects than topical (BV) 0.1% ointment. Keywords: Basic fibroblast growth factor {b FGF}. Betamethasone valerate 0.1% ointment. Vitiligo. White depigmented patches." @default.
- W2289740840 created "2016-06-24" @default.
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- W2289740840 date "2015-07-06" @default.
- W2289740840 modified "2023-09-27" @default.
- W2289740840 title "Comparative Study Of Efficacy and Safety of Topical Active Fragment of Basic Fibroblast Growth Factor (B FGF) 0.1% Solution V/S Betamethasone Valerate 0.1% Ointment in the Treatment of Vitiligo Patients" @default.
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- W2289740840 doi "https://doi.org/10.6084/m9.figshare.1473035.v1" @default.
- W2289740840 hasPublicationYear "2015" @default.
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