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- W2289920203 abstract "Summary The effects of natural and synthetic detergents (sodium taurocholate, bile, decyl sulfate) and urea in breaking the gastric mucosal barrier were studied by irrigating the separated, vagally denervated pouches of the oxyntic glandular area of the dog stomach first with a test solution of 100 mm HCl + 54 mm NaCl, then with a solution of the detergent or urea, and again with the acid test solution. Fluxes of Na + , K + , and H + were measured, and changes over the control fluxes were taken as evidence that the barrier had been broken. Bile salts (10, 20, and 40 mm in neutral solution, 40 mm in a liquid meal, and 10 mm in acid solution), decyl sulfate (10 or 20 mm in neutral solution), and urea (1, 2, and 4 lvt in neutral solution) all break the gastric mucosal barrier." @default.
- W2289920203 created "2016-06-24" @default.
- W2289920203 creator A5088215668 @default.
- W2289920203 date "1968-02-01" @default.
- W2289920203 modified "2023-10-16" @default.
- W2289920203 title "Destruction of the Gastric Mucosal Barrier by Detergents and Urea" @default.
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- W2289920203 doi "https://doi.org/10.1016/s0016-5085(68)80001-0" @default.
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