Matches in SemOpenAlex for { <https://semopenalex.org/work/W2290017634> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2290017634 abstract "Idiopathic inflammatory myopathies are usually regarded as a heterogeneous group of autoimmune rheumatic diseases. Dermatomyositis and polymyositis may affect children and adults and, although rare, are a major cause of disability. In order to assess the value of conventional and newer therapies, a core set of measures for assessing myositis outcomes are being developed . This thesis reports on the design and analysis of two real patient exercises carried out to study proposed measures. An approach to the study of reliability and agreement is presented. Inference procedures for ratios of standard errors are developed. The myostitis measures are based on previous work in systemic lupus erythematosus (lupus), a major autoimmune rheumatic disease. International attempts to define validated disease activity and damage indices to assess patients with lupus have provided a consistent way to assess the disease. However, its multiple clinical manifestations prove a great challenge to rheumatologists managing patients with lupus. There is a need to better understand predictors of disease activity in order to improve and standardize therapy and to prevent the development of chronic damage. This thesis presents an analysis of a clinical database for patients with lupus. The aim is to develop approaches to examine the interrelationships between disease activity in the different organ systems. The database available for analysis consists of data collected on 440 patients over a period of 10 years. The analysis is based on logistic regression methodology with outcomes defined at the times of clinic visits. The usefulness of separate logistic regressions with dynamic covariates for the analysis of multinomial panel data is illustrated. The efficiency of the approach relative to modelling disease activity in continuous time is investigated." @default.
- W2290017634 created "2016-06-24" @default.
- W2290017634 creator A5046785047 @default.
- W2290017634 date "2004-01-01" @default.
- W2290017634 modified "2023-09-28" @default.
- W2290017634 title "Multi-organ rheumatological disease: Statistical analysis of outcome measures and their interrelationships." @default.
- W2290017634 hasPublicationYear "2004" @default.
- W2290017634 type Work @default.
- W2290017634 sameAs 2290017634 @default.
- W2290017634 citedByCount "0" @default.
- W2290017634 crossrefType "dissertation" @default.
- W2290017634 hasAuthorship W2290017634A5046785047 @default.
- W2290017634 hasConcept C126322002 @default.
- W2290017634 hasConcept C151956035 @default.
- W2290017634 hasConcept C177713679 @default.
- W2290017634 hasConcept C1862650 @default.
- W2290017634 hasConcept C2776912625 @default.
- W2290017634 hasConcept C2778751314 @default.
- W2290017634 hasConcept C2779134260 @default.
- W2290017634 hasConcept C2779387793 @default.
- W2290017634 hasConcept C2781232998 @default.
- W2290017634 hasConcept C71924100 @default.
- W2290017634 hasConceptScore W2290017634C126322002 @default.
- W2290017634 hasConceptScore W2290017634C151956035 @default.
- W2290017634 hasConceptScore W2290017634C177713679 @default.
- W2290017634 hasConceptScore W2290017634C1862650 @default.
- W2290017634 hasConceptScore W2290017634C2776912625 @default.
- W2290017634 hasConceptScore W2290017634C2778751314 @default.
- W2290017634 hasConceptScore W2290017634C2779134260 @default.
- W2290017634 hasConceptScore W2290017634C2779387793 @default.
- W2290017634 hasConceptScore W2290017634C2781232998 @default.
- W2290017634 hasConceptScore W2290017634C71924100 @default.
- W2290017634 hasLocation W22900176341 @default.
- W2290017634 hasOpenAccess W2290017634 @default.
- W2290017634 hasPrimaryLocation W22900176341 @default.
- W2290017634 hasRelatedWork W1989946887 @default.
- W2290017634 hasRelatedWork W2020344612 @default.
- W2290017634 hasRelatedWork W2043329185 @default.
- W2290017634 hasRelatedWork W2046236592 @default.
- W2290017634 hasRelatedWork W2114794847 @default.
- W2290017634 hasRelatedWork W2127898541 @default.
- W2290017634 hasRelatedWork W2139701419 @default.
- W2290017634 hasRelatedWork W2171889708 @default.
- W2290017634 hasRelatedWork W2181978752 @default.
- W2290017634 hasRelatedWork W2251694322 @default.
- W2290017634 hasRelatedWork W2271143443 @default.
- W2290017634 hasRelatedWork W2315502763 @default.
- W2290017634 hasRelatedWork W2407817785 @default.
- W2290017634 hasRelatedWork W2509330524 @default.
- W2290017634 hasRelatedWork W2800342464 @default.
- W2290017634 hasRelatedWork W2807157443 @default.
- W2290017634 hasRelatedWork W3110286809 @default.
- W2290017634 hasRelatedWork W3164086838 @default.
- W2290017634 hasRelatedWork W380766533 @default.
- W2290017634 hasRelatedWork W2419502033 @default.
- W2290017634 isParatext "false" @default.
- W2290017634 isRetracted "false" @default.
- W2290017634 magId "2290017634" @default.
- W2290017634 workType "dissertation" @default.