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• W2290068333 abstract "The basal ganglia are large subcortical nuclei, mainly concerned with somatic motor function. The amygdaloid nucleus is functionally related to the limbic system. The other basal ganglia comprise the corpus striatum, globus pallidus, subthalamic nucleus, and substantia nigra. The basal ganglia play an important part in the initiation of movement, the control of ramp movements, the change from one pattern of movement to another, and righting reflexes. Parkinson's disease is a degenerative disorder, the main brunt of which falls on the basal ganglia, chiefly the substantia nigra. Parkinson's disease commonly presents with difficulty in using one arm for skilled movement, dragging one foot when walking, or the complaint of aching in the affected limbs. The arm may not swing freely on walking and careful examination will disclose the presence of cog­wheel rigidity on the affected side. Bradykinesia means slowness in initiating or performing movements, which is a common symptom of Parkinson's disease irrespective of the degree of rigidity present. Parkinson patients have a longer reaction time than normal controls for initiating movements and for stopping or correcting movements in progress. The rigidity of Parkinson's disease is caused by an increase in tonic stretch reflexes with certain characteristics that distinguish it from the spasticity of upper motor neuron lesions." @default.
• W2290068333 created "2016-06-24" @default.
• W2290068333 creator A5036571547 @default.
• W2290068333 date "1981-01-01" @default.
• W2290068333 modified "2023-09-25" @default.
• W2290068333 title "The basal ganglia and their disorders" @default.
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• W2290068333 doi "https://doi.org/10.1016/b978-0-407-00196-1.50013-9" @default.
• W2290068333 hasPublicationYear "1981" @default.
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