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- W2290141228 abstract "BACKGROUND. Recently, 1-octanol has been shown to have efficacy in treating patients with essential tremor (ET). The primary metabolite of 1-octanol is octanoic acid (OA), which is now thought to be the active substance that mediates tremor suppression. Our aim was to describe the maximum tolerated dose (MTD) of oral OA in patients with ET and assess the pharmacokinetics (PK) and pharmacodynamics (PD) profile of OA." @default.
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- W2290141228 date "2016-02-29" @default.
- W2290141228 modified "2023-09-27" @default.
- W2290141228 title "Dose-escalation study of octanoic acid in patients with essential tremor" @default.
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- W2290141228 doi "https://doi.org/10.1172/jci83621" @default.
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