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- W2290394071 endingPage "1934578X0600100" @default.
- W2290394071 startingPage "1934578X0600100" @default.
- W2290394071 abstract "Although acetylenes are common as components of terrestrial plants, it is only within the last 30 years that biologically active polyacetylenes having unusual structural features have been reported from aquatic organisms: cyanobacteria, algae, fungi, invertebrates, and other sources. Naturally occurring aquatic acetylenes are of particular interest since many of them display important biological activities and possess antitumor, antibacterial, antimicrobial, antifouling, antifungal, pesticidal, phototoxic, HIV inhibitory, and immuno-suppressive properties. There is no doubt that they are of great interest, especially for the medicinal and/or pharmaceutical industries. This review presents structures and describes cytotoxic and anticancer activities of more than 230 acetylenic metabolites isolated from aquatic organisms. With the computer program PASS some additional biological activities are also predicted, which point toward possible new applications of these compounds. This review emphasizes the role of aquatic acetylenic compounds as an important source of leads for drug discovery." @default.
- W2290394071 created "2016-06-24" @default.
- W2290394071 creator A5014517698 @default.
- W2290394071 creator A5022787716 @default.
- W2290394071 creator A5029121475 @default.
- W2290394071 creator A5032596931 @default.
- W2290394071 date "2006-09-01" @default.
- W2290394071 modified "2023-10-11" @default.
- W2290394071 title "Acetylenic Aquatic Anticancer Agents and Related Compounds" @default.
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