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- W2290521188 abstract "16 The objective was to compare endometrial gene expression profiles in a group of beef 17 heifers yielding viable or degenerate embryos on Day 7 after oestrus as a means to 18 potentially explain differences in embryo survival rates. The focus was on genes that were 19 associated with either the proor anti-inflammatory immune response. Endometrial gene 20 expression was determined using q-RT-PCR analysis. Expression of Beta defensin 21 (DEFB), Interferon alpha (IFN), Interferon gamma (IFN), Interleukin 6 (IL6), 22 Interleukin 10 (IL10), Forkhead box P3 (FOXP3) and Natural cytotoxicity triggering 23 receptor 1 (NCR1) was lower in endometria from heifers that produced viable embryos 24 compared with those that produced retarded embryos. Expression of Nuclear factor of 25 kappa light polypeptide gene enhancer in B-cells 1 (NKFB1), Transforming growth factor 26 beta (TGF Interferon gamma-inducible protein 16 (IFI16) and Interleukin 21 (IL21) 27 was higher in viable than in retarded heifers. We propose that small disturbances in the 28 expression of immune genes in the endometrium on Day 7 after estrus can have 29 detrimental effects on embryonic survival. 30" @default.
- W2290521188 created "2016-06-24" @default.
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- W2290521188 date "2016-01-01" @default.
- W2290521188 modified "2023-09-27" @default.
- W2290521188 title "Title Altered endometrial immune gene expression in beef heifers with retarded embryos" @default.
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