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• W2290584799 abstract "Abstract Trends in the incidence of cancer in the population of Kyadondo County, Uganda—which comprises the city of Kampala and a peri‐urban hinterland—are presented for a period of 25 years (1991‐2015) based on data collected by the Kampala Cancer Registry. Incidence rates have risen overall—age‐adjusted rates are some 25% higher in 2011 to 2015 compared with 1991 to 1995. The biggest absolute increases have been in cancers of the prostate, breast and cervix, with rates of some 100% (prostate), 70% (breast) and 45% (cervix) higher in 2010 to 2015 than in 1991 to 1995. There were also increases in the incidence of cancers of the esophagus and colon‐rectum (statistically significant in men), while the incidence of liver cancer—the fifth most common in this population—increased until 2007, and subsequently declined. By far the most commonly registered cancer over the 25‐year period was Kaposi sarcoma, but the incidence has declined, consistent with the decreasing population‐prevalence of HIV. Non‐Hodgkin lymphomas, also AIDS‐related, increased in incidence until 2006/2007 and then declined—possibly as a result of availability of antiretroviral therapy. The trends reflect the changing lifestyles of this urban African population, as well as the consequences of the epidemic of HIV/AIDS and the availability of treatment with ARVs. At the same time, it highlights the fact that the decreases in cancer of the cervix observed in high and upper‐middle income countries are not a consequence of changes in lifestyle, but demand active intervention through screening (and, in the longer term, vaccination)." @default.
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• W2290584799 date "2020-11-29" @default.
• W2290584799 modified "2023-10-16" @default.
• W2290584799 title "Trends in the incidence of cancer in Kampala, Uganda, 1991 to 2015" @default.
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• W2290584799 doi "https://doi.org/10.1002/ijc.33373" @default.
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