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- W2290653917 abstract "A simple, green, efficient and economical procedure for the synthesis of , pyrano[3,2-c]chromene derivatives by using a one-pot three-component condensation of 4-Hydroxycoumarin, various arylaldehydes and malonitrile in 1-butyl-3-methylimidazolium triflate as green media is described. This reaction proceeded under mild conditions with the use of an inexpensive and readily available catalyst, high to excellent yields, and simple workup procedure. In addition; the compounds 5 were investigated for anti-oxidant activities by super oxide radical; DPPH (2,2-Diphenyl-1-picrylhydrazyl); and hydroxyl radical scavenging assays; in which most of them displayed significant antioxidant activities. Furthermore; compounds 5 were evaluated for anti-inflammatory activity by indirect haemolytic and lipoxygenase inhibition assays and revealed good activity. Most of the new compounds 5 exhibited moderate antibacterial activity." @default.
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- W2290653917 date "2016-03-02" @default.
- W2290653917 modified "2023-09-28" @default.
- W2290653917 title "Novel pyrano[3,2-c]chromene derivatives via a green one-pot three component: Synthesis, characterization , antioxidant, antibacterial and anti-inflammatory activities" @default.
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