FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2290821459> ?p ?o ?g. }

• W2290821459 endingPage "72" @default.
• W2290821459 startingPage "665" @default.
• W2290821459 abstract "To measure intravitreal low-density lipoprotein receptor-related protein 6 (LRP6) and vascular endothelial growth factor (VEGF) levels in the eyes of patients with proliferative diabetic retinopathy (PDR) and to observe their correlation with PDR activity.Fifty-five eyes of 55 patients were enrolled consecutively. Vitreous samples from 30 eyes with PDR and 25 eyes with nondiabetic macular disease were collected. Active PDR was present in 16 patients and quiescent PDR in 14 patients according to retinal neovascularization. LRP6 and VEGF concentrations in samples were determined using enzyme-linked immunosorbent assay (ELISA).ELISA revealed significant increases in the vitreous levels of VEGF in eyes affected with PDR compared to the controls (p<0.001). The mean concentrations of LRP6 were also higher in the vitreous samples from patients with PDR compared to the nondiabetic controls: 39.85 ng/ml and 15.48 ng/ml, respectively (p=0.002). In addition, the vitreous levels of LRP6 and VEGF were significantly higher in active PDR than in quiescent PDR (p=0.022 and p=0.015, respectively). Furthermore, a significant positive correlation was found between intravitreal levels of LRP6 and VEGF in patients with PDR (r=0.567, p=0.001). However, comparison of patients with PDR with controls revealed that the plasma levels of LRP6 were not significantly different between the two groups (p=0.636).LRP6 and VEGF levels in the vitreous body from patients with PDR were increased and correlated mutually. LRP6 may be a good diagnostic biomarker and a new therapeutic target for PDR." @default.
• W2290821459 created "2016-06-24" @default.
• W2290821459 creator A5005445343 @default.
• W2290821459 creator A5010952178 @default.
• W2290821459 creator A5037816762 @default.
• W2290821459 creator A5042846805 @default.
• W2290821459 creator A5067568342 @default.
• W2290821459 creator A5072552137 @default.
• W2290821459 date "2015-01-01" @default.
• W2290821459 modified "2023-10-16" @default.
• W2290821459 title "Elevated LRP6 levels correlate with vascular endothelial growth factor in the vitreous of proliferative diabetic retinopathy." @default.
• W2290821459 cites W1780615788 @default.
• W2290821459 cites W1894783768 @default.
• W2290821459 cites W1971837252 @default.
• W2290821459 cites W1977755136 @default.
• W2290821459 cites W1980527184 @default.
• W2290821459 cites W1981996695 @default.
• W2290821459 cites W2000293457 @default.
• W2290821459 cites W2002025697 @default.
• W2290821459 cites W2004918005 @default.
• W2290821459 cites W2007443629 @default.
• W2290821459 cites W2020835608 @default.
• W2290821459 cites W2028561648 @default.
• W2290821459 cites W2039407102 @default.
• W2290821459 cites W2054226501 @default.
• W2290821459 cites W2061356986 @default.
• W2290821459 cites W2083158448 @default.
• W2290821459 cites W2084225291 @default.
• W2290821459 cites W2088292685 @default.
• W2290821459 cites W2098942350 @default.
• W2290821459 cites W2113755481 @default.
• W2290821459 cites W2114112168 @default.
• W2290821459 cites W2119048927 @default.
• W2290821459 cites W2134856187 @default.
• W2290821459 cites W2141445274 @default.
• W2290821459 cites W2142636456 @default.
• W2290821459 cites W2146139435 @default.
• W2290821459 cites W2157313762 @default.
• W2290821459 cites W2159265947 @default.
• W2290821459 cites W2163948758 @default.
• W2290821459 cites W2324588265 @default.
• W2290821459 cites W4206790091 @default.
• W2290821459 cites W47656108 @default.
• W2290821459 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4462953" @default.
• W2290821459 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26120271" @default.
• W2290821459 hasPublicationYear "2015" @default.
• W2290821459 type Work @default.
• W2290821459 sameAs 2290821459 @default.
• W2290821459 citedByCount "7" @default.
• W2290821459 countsByYear W22908214592017 @default.
• W2290821459 countsByYear W22908214592019 @default.
• W2290821459 countsByYear W22908214592020 @default.
• W2290821459 countsByYear W22908214592021 @default.
• W2290821459 countsByYear W22908214592022 @default.
• W2290821459 crossrefType "journal-article" @default.
• W2290821459 hasAuthorship W2290821459A5005445343 @default.
• W2290821459 hasAuthorship W2290821459A5010952178 @default.
• W2290821459 hasAuthorship W2290821459A5037816762 @default.
• W2290821459 hasAuthorship W2290821459A5042846805 @default.
• W2290821459 hasAuthorship W2290821459A5067568342 @default.
• W2290821459 hasAuthorship W2290821459A5072552137 @default.
• W2290821459 hasConcept C118487528 @default.
• W2290821459 hasConcept C126322002 @default.
• W2290821459 hasConcept C134018914 @default.
• W2290821459 hasConcept C167734588 @default.
• W2290821459 hasConcept C185592680 @default.
• W2290821459 hasConcept C2777025900 @default.
• W2290821459 hasConcept C2778271429 @default.
• W2290821459 hasConcept C2778313320 @default.
• W2290821459 hasConcept C2779829184 @default.
• W2290821459 hasConcept C2780394083 @default.
• W2290821459 hasConcept C2781197716 @default.
• W2290821459 hasConcept C55493867 @default.
• W2290821459 hasConcept C555293320 @default.
• W2290821459 hasConcept C71924100 @default.
• W2290821459 hasConceptScore W2290821459C118487528 @default.
• W2290821459 hasConceptScore W2290821459C126322002 @default.
• W2290821459 hasConceptScore W2290821459C134018914 @default.
• W2290821459 hasConceptScore W2290821459C167734588 @default.
• W2290821459 hasConceptScore W2290821459C185592680 @default.
• W2290821459 hasConceptScore W2290821459C2777025900 @default.
• W2290821459 hasConceptScore W2290821459C2778271429 @default.
• W2290821459 hasConceptScore W2290821459C2778313320 @default.
• W2290821459 hasConceptScore W2290821459C2779829184 @default.
• W2290821459 hasConceptScore W2290821459C2780394083 @default.
• W2290821459 hasConceptScore W2290821459C2781197716 @default.
• W2290821459 hasConceptScore W2290821459C55493867 @default.
• W2290821459 hasConceptScore W2290821459C555293320 @default.
• W2290821459 hasConceptScore W2290821459C71924100 @default.
• W2290821459 hasLocation W22908214591 @default.
• W2290821459 hasOpenAccess W2290821459 @default.
• W2290821459 hasPrimaryLocation W22908214591 @default.
• W2290821459 hasRelatedWork W2010856132 @default.
• W2290821459 hasRelatedWork W2054235453 @default.
• W2290821459 hasRelatedWork W2058480763 @default.
• W2290821459 hasRelatedWork W2091598664 @default.
• W2290821459 hasRelatedWork W2265567290 @default.
• W2290821459 hasRelatedWork W2367206690 @default.

• next