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- W2290871090 abstract "Mary Jane EsplenIntroduction and BackgroundThe Human Genome Project is a fast-developing area of health researchthat is leading to new ways of dealing with health and disease.The infor-mation and technology gained as a result of the Human Genome Projectare expected to have a profound impact on individuals and society.Thispaper highlights Canadian research initiatives related to genetics,including the implications of such research for nursing.Until recent developments in the Þeld,geneticists mainly dealt withrare disorders and prenatal or pediatric populations.To this area ofpractice has been added counselling and testing for adult-onset heredi-tary disorders,whereby individuals may be provided with informationabout their own risk for disease.Hereditary diseases include,amongothers,cancers (e.g.,breast,ovarian,and colorectal),cardiovascular disease,diabetes,and some neurodegenerative diseases such as Alzheimer diseaseand Huntington disease.Genetic advances are leading to new approachesin the assessment of disease risk and in prevention recommendations forhealthy individuals (Burke et al.,1997).Genetic treatments and preven-tion strategies are already being integrated into clinical medicine;thistrend will continue over the coming decades as translation of researchÞndings becomes possible for a wider and wider range of conditions.Biomedical advances are increasing our understanding of genetic differ-ences in pharmacological sensitivity among individuals,leading to thetailoring of medications based on inherited characteristics (Evans &Relling,1999).Preventive or surveillance interventions will be speciÞ-cally targeted to those at greatest risk,with the goal of reducing theincidence and mortality of disease.As well,careful assessment of healthbehaviours (e.g.,with regard to smoking,diet,exercise,use of oral contra-ceptives) and biomedical and genetic factors in those at increased geneticrisk will be a greater focus in nursing care.CJNR 2006,Vol.38 N" @default.
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- W2290871090 date "2006-01-01" @default.
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- W2290871090 title "Happenings Mapping the Human Genome: Psychosocial Impacts and Implications for Nursing" @default.
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