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- W2290973885 endingPage "2502" @default.
- W2290973885 startingPage "2483" @default.
- W2290973885 abstract "Abstract Over the last decade, the state‐of‐the‐art in cardiac computational modelling has progressed rapidly. The electrophysiological function of the heart can now be simulated with a high degree of detail and accuracy, opening the doors for simulation‐guided approaches to anti‐arrhythmic drug development and patient‐specific therapeutic interventions. In this review, we outline the basic methodology for cardiac modelling, which has been developed and validated over decades of research. In addition, we present several recent examples of how computational models of the human heart have been used to address current clinical problems in cardiac electrophysiology. We will explore the use of simulations to improve anti‐arrhythmic pacing and defibrillation interventions; to predict optimal sites for clinical ablation procedures; and to aid in the understanding and selection of arrhythmia risk markers. Together, these studies illustrate how the tremendous advances in cardiac modelling are poised to revolutionize medical treatment and prevention of arrhythmia. image" @default.
- W2290973885 created "2016-06-24" @default.
- W2290973885 creator A5051580093 @default.
- W2290973885 creator A5070924694 @default.
- W2290973885 date "2016-01-18" @default.
- W2290973885 modified "2023-10-03" @default.
- W2290973885 title "How computer simulations of the human heart can improve anti-arrhythmia therapy" @default.
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