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- W2291222587 abstract "In this study, the antibacterial, antioxidative and inhibitory effects of Allium cepa peel extracts on tyrosinase and elastase were investigated. MIC values of the ethyl acetate fraction of Allium cepa peel on especially, S. aureus among the skin resi- dent flora (Staphylococcus aureus, S. aureus; Propionibacterium acnes, P. acnes; Pityrosporum ovale, P. ovale; Escherichia coli, E. coli) were 0.06%. The aglycone fraction showed more excellent free radical (1,1-diphenyl-2-picrylhydrazyl radical, DPPH) scavenging activity (FSC50 = 5.05 µg/mL). Reactive oxygen species (ROS) scavenging activities (OSC50) of the ethyl acetate fraction and aglycone fraction in the luminol-dependent Fe 3+ -EDTA/H2O2 system were 0.05 and 0.03 µg/mL, respectively. The cellular protective effect of the aglycone fraction on the rose-bengal sensitized photohemolysis of human erythrocytes exhibited more prominent (τ50, 480 min at 25 µg/mL). The inhibitory effects (IC50) of the ethyl acetate fraction and aglycone fraction on tyrosinase were 9.16 and 8.68 µg/mL, the inhibitory effect (IC50) of the aglycone fraction on elastase was 14.12 µg/mL The transepidermal water loss of the cream containing 0.1% ethyl acetate fraction was decreased from 8.3 g/m 2 h in control to 6.8 g/m 2 h in the subjects applied with cream containing the ethyl acetate fraction. These results in- dicate that extract/fractions of Allium cepa peel can function as antioxidant in biological systems, particularly skin exposed to UV radiation by scavenging 1 O2 and other ROS, and protect cellular membranes against ROS, and possibly as antiaging agents. Allium cepa peel extract could be used as a new cosmeceutical for whitening and anti-wrinkle products." @default.
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- W2291222587 date "2011-01-01" @default.
- W2291222587 modified "2023-09-23" @default.
- W2291222587 title "Antibacterial, Antioxidative and Antiaging Effects of Allium cepa Peel Extracts" @default.
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