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- W2291246110 abstract "The occurrence of chromanone derivatives has been noticed as a distinctive feature of the genus Calophyllum (Calophyllaceae). Previous studies have demonstrated that the extract of the stem bark of Calophyllum brasiliense and its chromanone-rich fractions show anti-ulcer activity in murine gastric ulcer models. In this work, brasiliensic and isobrasiliensic acids, the two main compounds of the n-hexane extract of the stem bark extract of C. brasiliense, were isolated by flash chromatography using silica gel impregnated with silver nitrate and their structures were elucidated by NMR techniques and mass spectrometry. 13C NMR data is available for the first time for both compounds. Brasiliensic and isobrasiliensic acids showed good in vitro bacteriostatic activity against Helicobacter pylori, and are responsible, at least in part, for the bacteriostatic anti-H. pylori activity of the n-hexane extract of the stem bark of C. brasiliense." @default.
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- W2291246110 date "2016-02-15" @default.
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- W2291246110 title "Brasiliensic and isobrasiliensic acids: isolation from <i>Calophyllum brasiliense</i> Cambess. and anti-<i>Helicobacter pylori</i> activity" @default.
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- W2291246110 doi "https://doi.org/10.1080/14786419.2015.1137568" @default.
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