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- W2291418903 abstract "[背景]吸入细颗粒物（颗粒物直径≤2.5μm,PM2.5）能诱发氧化应激和炎症反应,并有可能导致早产和其他不良的围产期结局。[目的]检测2004—2008年,世界卫生组织在全球22个国家中进行的孕产妇和围产期保健调查中,室外PM2.5是否与不良妊娠结局相关。[方法]以有新生儿出生的各医疗诊所周围50 km为半径的圆弧缓冲区计算室外PM2.5的长期均值（2001—2006年）。应用广义估计方程确定诊所的PM2.5水平与个体的早产和低出生体重之间的相关性,调整个人、诊所和国家水平的季节性因素及潜在的混杂因素。另外还对各国中的相关性进行了研究。[结果]在所有国家中,调整季节性因素后,PM2.5与早产无关联,但是与低出生体重相关[PM2.5的第四个四分位数段（〉20.2μg/m3）与第一个四分位数（〈6.3μg/m3）相比,比值比（OR）=1.22;95%CI：1.07-1.39]。中国是PM2.5测量值范围最大的国家,早产和低出生体重均仅与PM2.5的最高四分位数段相关,提示可能存在阈值效应（PM2.5≥36.5μg/m3与PM2.5〈12.5μg/m3相比,早产和低出生体重比值比分别为：OR=2.54;CI：1.42-4.55和OR=1.99;CI：1.06-3.72）。[结论]室外PM2.5浓度与低出生体重相关,但与早产不相关。在快速发展的国家中,例如中国,最高的空气污染水平可能与两个结局都相关。" @default.
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- W2291418903 date "2014-01-01" @default.
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- W2291418903 title "室外空气污染、早产和低出生体重：世界卫生组织孕产妇和围产期保健全球调查分析" @default.
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