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- W2291520406 abstract "Purpose: Response to iniximab treatment diminishes as body mass index (BMI) increases in patients with ankylosing spondylitis (AS). �e purpose of the study was to determine if diminished response to iniximab treatment in patients with AS could be associated with increased visceral adipose tissue rather than increased BMI. Methods: Twenty six AS patients (21 males andve females) who fullled the modied New York criteria and who were currently receiving iniximab treatment were enrolled in the study. Pain was measured by the visual analogue scale (VAS). �e disease activity and functional status were assessed by the Bath AS Disease Activity Index (BASDAI) and the Bath AS Functional Index (BASFI). �e Bath AS Metrology Index (BASMI) was used to evaluate mobility restrictions. Weight and visceral body composition were measured with- out shoes in light indoor clothes using a bio-impedance meter. Results: �ere was a signicant correlation between visceral adipose tissue amount and disease activity under iniximab treatment. In correlation analysis, visceral fat showed sig- nicant correlations between BASDAI (r=0.545, p=0.004) and VAS (r=0.458, p=0.019). Total body fat also showed a signicant correlation with BASDAI (r=0.463, p=0.017). Conclusion: A signicant correlation was found between visceral adipose tissue amount and disease activity in patients with AS." @default.
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- W2291520406 date "2014-01-01" @default.
- W2291520406 modified "2023-09-22" @default.
- W2291520406 title "Visceral Fat Reects Disease Activity in Patients with Ankylosing Spondylitis" @default.
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