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- W2292121144 abstract "OBJECTIVE To investigate the distribution of excretion pump gene related to antibiosis praeparatum(biocide,sanitizer,antibacterials) in 20 clinical isolates of multidrug-resistant klebsiella pneumoniae(MDR-KPN).METHODS Four excretion pump genes(mdfA,tehA,smr,qacE△1) related to antibiosis praeparatum in 20 clinical isolates of MDR-KPN were assayed by polymerase chain reaction(PCR).RESULTS Among 20 strains of MDR-KPN,the positive rates of mdfA,tehA,smr,qacE△1 were 85.0%,5.0%,20.0% and 75.0%,respectively and the positive rate of mdfA,qacE△1 were very high.Most of the MDR-KPN strains carryied more than one excretion pump genes.It first reported that mdfA,tehA,smr were found in MDR-KPN domesticly.CONCLUSIONS Excretion pump gene are mostly found in MDR-KPN.mdfA,qacE△1 may be the main excretion pump gene which induce mutlti-resistant mechanism of MDR-KPN in our hospital.It is important to develop new inhibitor for the high excretion pump gene positive rate." @default.
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- W2292121144 date "2010-01-01" @default.
- W2292121144 modified "2023-09-24" @default.
- W2292121144 title "Detection of Excretion Pump Gene Related to Antibiotics Praeparatum in Multidrug-resistant Klebsiella pneumoniae" @default.
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