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- W2292140866 abstract "RESEARCH DESIGN AND METHODS — This analysis is based on data from the base- line (1989-1992) and first follow-up (1994-1995) examinations of the Strong Heart Study. The 1,581 diabetic participants included in this analysis were aged 45-74 years at baseline, were diagnosed with diabetes before and at baseline, and had their HbA1 c levels measured at follow- up. HbA1c was used as the index of glycemic control. Characteristics that may affect glycemic c o n t rol were evaluated for cross-sectional and longitudinal relationships by analysis of covari- ance and multiple re g re s s i o n . R E S U LT S — T h e re was no significant diff e rence between median HbA1c at baseline (8.4%) and at follow-up (8.5%). Sex, age (inversely), and insulin and oral hypoglycemic agent ther- apy were significantly related to HbA1 c levels in both the cross-sectional and longitudinal analy- ses. Current smoking, prior use of alcohol, and duration of diabetes were significant only for the cross-sectional data. Baseline HbA1 c s i g n i ficantly and positively predicted HbA1 c levels at follow-up. Comparison of HbA1 c by therapy type shows that insulin therapy produced a signifi- cant decrease in HbA1 c between the baseline and follow-up examinations. C O N C L U S I O N S — Glycemic control was poor among diabetic American Indians part i c- ipating in the Strong Heart Study. Women, patients taking insulin or oral hypoglycemic agents, and younger individuals had the worst control of all the participants. Baseline HbA1 c, and weight loss predicted worsening of control, whereas insulin therapy predicted impro v e m e n t in control. Additional therapies and/or approaches are needed to improve glycemic control in this population." @default.
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- W2292140866 date "1999-01-01" @default.
- W2292140866 modified "2023-09-23" @default.
- W2292140866 title "Glycemic Control in Diabetic American I n d i a n s" @default.
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