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- W2292251010 abstract "Neurons of the corticospinal tract are inherently sensitive to oxygen availability and, in response to hypoxia, reduce their metabolic requirements and activity [1]. Consequently, hypoxia is associated with neuromuscular fatigue, attributed in part to central (i.e., CNS) mechanisms [2]. Although changes in cerebral blood flow (CBF), mediated by the ratio of hypoxia induced vasodilation to hypoxic ventilatory response (HVR) induced hypocapnia (i.e., PETCO2) [3], may be implicated in the development of central fatigue, the contribution from the chemoreflex control of HVR and CBF vs. reductions in CBF per se has yet to be isolated." @default.
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- W2292251010 date "2015-09-14" @default.
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- W2292251010 title "Neuromuscular fatigue during hypoxia is mediated by the hypoxic ventilatory response" @default.
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- W2292251010 doi "https://doi.org/10.1186/2046-7648-4-s1-a41" @default.
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