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- W2292969439 abstract "The neurodegenerative and inflammatory environment that is prevalent in the diabetic eye is a key player in the development and progression of diabetic retinopathy. The adenosinergic system is widely regarded as a significant modulator of neurotransmission and the inflammatory response, through the actions of the four types of adenosine receptors (A 1 R, A 2A R, A 2B R, and A 3 R), and thus could be revealed as a potential player in the events unfolding in the early stages of diabetic retinopathy. Herein, we review the studies that explore the impact of diabetic conditions on the retinal adenosinergic system, as well as the role of the said system in ameliorating or exacerbating those conditions. The experimental results described suggest that this system is heavily affected by diabetic conditions and that the modulation of its components could reveal potential therapeutic targets for the treatment of diabetic retinopathy, particularly in the early stages of the disease." @default.
- W2292969439 created "2016-06-24" @default.
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- W2292969439 date "2016-01-01" @default.
- W2292969439 modified "2023-10-14" @default.
- W2292969439 title "The Adenosinergic System in Diabetic Retinopathy" @default.
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- W2292969439 doi "https://doi.org/10.1155/2016/4270301" @default.
- W2292969439 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4789509" @default.
- W2292969439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27034960" @default.
- W2292969439 hasPublicationYear "2016" @default.
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