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- W2293032852 abstract "Many diseases that originate on mucosal membranes ensue from the action of polymicrobial communities of indigenous organisms working in concert to disrupt homeostatic mechanisms. Multilevel physical and chemical communication systems among constituent organisms underlie polymicrobial synergy and dictate the community's pathogenic potential or nososymbiocity, that is, disease arising from living together with a susceptible host. Functional specialization of community participants, often originating from metabolic codependence, has given rise to several newly appreciated designations within the commensal-to-pathogen spectrum. Accessory pathogens, while inherently commensal in a particular microenvironment, nonetheless enhance the colonization or metabolic activity of pathogens. Keystone pathogens (bacterial drivers or alpha-bugs) exert their influence at low abundance by modulating both the composition and levels of community participants and by manipulating host responses. Pathobionts (or bacterial passengers) exploit disrupted host homeostasis to flourish and promote inflammatory disease. In this review we discuss how commensal or pathogenic properties of organisms are not intrinsic features, and have to be considered within the context of both the microbial community in which they reside and the host immune status." @default.
- W2293032852 created "2016-06-24" @default.
- W2293032852 creator A5008946134 @default.
- W2293032852 creator A5084031628 @default.
- W2293032852 date "2016-06-01" @default.
- W2293032852 modified "2023-10-17" @default.
- W2293032852 title "Dancing with the Stars: How Choreographed Bacterial Interactions Dictate Nososymbiocity and Give Rise to Keystone Pathogens, Accessory Pathogens, and Pathobionts" @default.
- W2293032852 cites W1483396672 @default.
- W2293032852 cites W1607743621 @default.
- W2293032852 cites W1699912176 @default.
- W2293032852 cites W1791865039 @default.
- W2293032852 cites W1859119857 @default.
- W2293032852 cites W1938827771 @default.
- W2293032852 cites W1966637161 @default.
- W2293032852 cites W1967309573 @default.
- W2293032852 cites W1968482421 @default.
- W2293032852 cites W1971730018 @default.
- W2293032852 cites W1979217507 @default.
- W2293032852 cites W1985434563 @default.
- W2293032852 cites W1987375206 @default.
- W2293032852 cites W1990473825 @default.
- W2293032852 cites W1995667568 @default.
- W2293032852 cites W1995924556 @default.
- W2293032852 cites W2001439699 @default.
- W2293032852 cites W2004413279 @default.
- W2293032852 cites W2004945352 @default.
- W2293032852 cites W2005194920 @default.
- W2293032852 cites W2008294135 @default.
- W2293032852 cites W2009938323 @default.
- W2293032852 cites W2020913417 @default.
- W2293032852 cites W2024661770 @default.
- W2293032852 cites W2025019766 @default.
- W2293032852 cites W2027763661 @default.
- W2293032852 cites W2029043977 @default.
- W2293032852 cites W2030631081 @default.
- W2293032852 cites W2040460416 @default.
- W2293032852 cites W2041432155 @default.
- W2293032852 cites W2043248182 @default.
- W2293032852 cites W2048270853 @default.
- W2293032852 cites W2050142214 @default.
- W2293032852 cites W2051208559 @default.
- W2293032852 cites W2052554412 @default.
- W2293032852 cites W2055251230 @default.
- W2293032852 cites W2059697362 @default.
- W2293032852 cites W2060711068 @default.
- W2293032852 cites W2062817953 @default.
- W2293032852 cites W2066013154 @default.
- W2293032852 cites W2068234766 @default.
- W2293032852 cites W2071116906 @default.
- W2293032852 cites W2073077653 @default.
- W2293032852 cites W2074150122 @default.
- W2293032852 cites W2080470002 @default.
- W2293032852 cites W2081653606 @default.
- W2293032852 cites W2082366901 @default.
- W2293032852 cites W2084120324 @default.
- W2293032852 cites W2088151791 @default.
- W2293032852 cites W2090443712 @default.
- W2293032852 cites W2090711340 @default.
- W2293032852 cites W2096233985 @default.
- W2293032852 cites W2098159838 @default.
- W2293032852 cites W2100415806 @default.
- W2293032852 cites W2101565190 @default.
- W2293032852 cites W2102977594 @default.
- W2293032852 cites W2103561589 @default.
- W2293032852 cites W2107069650 @default.
- W2293032852 cites W2107369528 @default.
- W2293032852 cites W2110389012 @default.
- W2293032852 cites W2116527263 @default.
- W2293032852 cites W2119007673 @default.
- W2293032852 cites W2120502386 @default.
- W2293032852 cites W2123583755 @default.
- W2293032852 cites W2140683554 @default.
- W2293032852 cites W2143901124 @default.
- W2293032852 cites W2146766390 @default.
- W2293032852 cites W2151798187 @default.
- W2293032852 cites W2153537808 @default.
- W2293032852 cites W2155395286 @default.
- W2293032852 cites W2164091113 @default.
- W2293032852 cites W2166155263 @default.
- W2293032852 cites W2167591869 @default.
- W2293032852 cites W2167783345 @default.
- W2293032852 cites W2167927725 @default.
- W2293032852 cites W2169722961 @default.
- W2293032852 cites W2172095976 @default.
- W2293032852 cites W2185752871 @default.
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- W2293032852 doi "https://doi.org/10.1016/j.tim.2016.02.010" @default.
- W2293032852 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4874887" @default.
- W2293032852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26968354" @default.
- W2293032852 hasPublicationYear "2016" @default.
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