FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2293098307> ?p ?o ?g. }

• W2293098307 endingPage "14160" @default.
• W2293098307 startingPage "14153" @default.
• W2293098307 abstract "Our recent retrospective study revealed a significantly reduced risk of bladder cancer (BC) recurrence in men who received androgen deprivation therapy (ADT) for their prostate cancer. However, whether androgen receptor (AR) signals contributed to the preventive effect of ADT remained unclear because ADT could reduce serum estrogens as well. The purpose of this study is to investigate the associations between the expression of AR/estrogen receptors (ERs) and BC recurrence in patients treated with ADT. We immunohistochemically stained 72 BCs and 42 corresponding normal urothelial tissues. AR/ERα/ERβ were positive in 44(61%)/22(31%)/39(54%) tumors and 35(83%)/24(57%)/34(81%) corresponding normal urothelial tissues, respectively. There were no statistically significant correlations between AR/ERα/ERβ expression and clinicopathological features of BC. With a median follow-up of 31.3 months, 12 (43%) of 28 patients with AR-negative tumor versus 11 (23%) of 44 patients with AR-positive tumor experienced BC recurrence. Thus, patients with AR-positive tumor had a significantly lower risk of BC recurrence (P=0.031), compared with those with AR-negative tumor. Meanwhile, the expression of ERα/ERβ in tumors and that of AR/ERα/ERβ in normal urothelial tissues were not significantly correlated with BC recurrence. A multivariate analysis revealed AR positivity in tumors as an independent prognosticator (hazard ratio: 0.27; 95% confidence interval: 0.11-0.67) for BC recurrence. These results indicate that ADT prevents BC recurrence via the AR pathway, but not via the ERα/ERβ pathways." @default.
• W2293098307 created "2016-06-24" @default.
• W2293098307 creator A5005779693 @default.
• W2293098307 creator A5011152005 @default.
• W2293098307 creator A5011667213 @default.
• W2293098307 creator A5013308350 @default.
• W2293098307 creator A5040985959 @default.
• W2293098307 creator A5051739342 @default.
• W2293098307 creator A5059540059 @default.
• W2293098307 creator A5065613884 @default.
• W2293098307 creator A5068189444 @default.
• W2293098307 creator A5076462635 @default.
• W2293098307 creator A5081210650 @default.
• W2293098307 creator A5085955274 @default.
• W2293098307 date "2016-02-12" @default.
• W2293098307 modified "2023-10-16" @default.
• W2293098307 title "Expression of androgen receptor in non-muscle-invasive bladder cancer predicts the preventive effect of androgen deprivation therapy on tumor recurrence" @default.
• W2293098307 cites W1216083017 @default.
• W2293098307 cites W1491207647 @default.
• W2293098307 cites W1598862994 @default.
• W2293098307 cites W1633535281 @default.
• W2293098307 cites W1910581708 @default.
• W2293098307 cites W2024729279 @default.
• W2293098307 cites W2033775272 @default.
• W2293098307 cites W2035297454 @default.
• W2293098307 cites W2067964015 @default.
• W2293098307 cites W2068523052 @default.
• W2293098307 cites W2083061567 @default.
• W2293098307 cites W2083716686 @default.
• W2293098307 cites W2093274894 @default.
• W2293098307 cites W2098406898 @default.
• W2293098307 cites W2115156555 @default.
• W2293098307 cites W2115506560 @default.
• W2293098307 cites W2118553855 @default.
• W2293098307 cites W2124614719 @default.
• W2293098307 cites W2128660461 @default.
• W2293098307 cites W2129078297 @default.
• W2293098307 cites W2133481857 @default.
• W2293098307 cites W2134555283 @default.
• W2293098307 cites W2138662111 @default.
• W2293098307 cites W2142937869 @default.
• W2293098307 cites W2144000500 @default.
• W2293098307 cites W2147720628 @default.
• W2293098307 cites W2151043608 @default.
• W2293098307 cites W2158397011 @default.
• W2293098307 cites W2162909245 @default.
• W2293098307 cites W2171134450 @default.
• W2293098307 cites W2172164477 @default.
• W2293098307 cites W2215466275 @default.
• W2293098307 cites W2319008104 @default.
• W2293098307 cites W2917837889 @default.
• W2293098307 doi "https://doi.org/10.18632/oncotarget.7358" @default.
• W2293098307 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4924704" @default.
• W2293098307 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26885620" @default.
• W2293098307 hasPublicationYear "2016" @default.
• W2293098307 type Work @default.
• W2293098307 sameAs 2293098307 @default.
• W2293098307 citedByCount "37" @default.
• W2293098307 countsByYear W22930983072016 @default.
• W2293098307 countsByYear W22930983072017 @default.
• W2293098307 countsByYear W22930983072018 @default.
• W2293098307 countsByYear W22930983072019 @default.
• W2293098307 countsByYear W22930983072020 @default.
• W2293098307 countsByYear W22930983072021 @default.
• W2293098307 countsByYear W22930983072022 @default.
• W2293098307 countsByYear W22930983072023 @default.
• W2293098307 crossrefType "journal-article" @default.
• W2293098307 hasAuthorship W2293098307A5005779693 @default.
• W2293098307 hasAuthorship W2293098307A5011152005 @default.
• W2293098307 hasAuthorship W2293098307A5011667213 @default.
• W2293098307 hasAuthorship W2293098307A5013308350 @default.
• W2293098307 hasAuthorship W2293098307A5040985959 @default.
• W2293098307 hasAuthorship W2293098307A5051739342 @default.
• W2293098307 hasAuthorship W2293098307A5059540059 @default.
• W2293098307 hasAuthorship W2293098307A5065613884 @default.
• W2293098307 hasAuthorship W2293098307A5068189444 @default.
• W2293098307 hasAuthorship W2293098307A5076462635 @default.
• W2293098307 hasAuthorship W2293098307A5081210650 @default.
• W2293098307 hasAuthorship W2293098307A5085955274 @default.
• W2293098307 hasBestOaLocation W22930983071 @default.
• W2293098307 hasConcept C121608353 @default.
• W2293098307 hasConcept C126322002 @default.
• W2293098307 hasConcept C126894567 @default.
• W2293098307 hasConcept C134018914 @default.
• W2293098307 hasConcept C143998085 @default.
• W2293098307 hasConcept C2777899217 @default.
• W2293098307 hasConcept C2777911890 @default.
• W2293098307 hasConcept C2780192828 @default.
• W2293098307 hasConcept C2780352672 @default.
• W2293098307 hasConcept C502942594 @default.
• W2293098307 hasConcept C61367390 @default.
• W2293098307 hasConcept C71315377 @default.
• W2293098307 hasConcept C71924100 @default.
• W2293098307 hasConceptScore W2293098307C121608353 @default.
• W2293098307 hasConceptScore W2293098307C126322002 @default.
• W2293098307 hasConceptScore W2293098307C126894567 @default.
• W2293098307 hasConceptScore W2293098307C134018914 @default.
• W2293098307 hasConceptScore W2293098307C143998085 @default.

• next