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- W2293344453 abstract "Introduction: Iron deficiency anemia (IDA) is the most common hematologic problem and easily treated with oral ferrous sulfate. In diagnosis of IDA, the serum ferritin level is the most reliable factor. However, there is no definite cutoff value of serum ferritin for the termination of iron therapy. A small-scale retrospective study was therefore carried out to determine an appropriate level of serum ferritin. Methods: Forty-seven patients who were diagnosed with IDA and treated with oral ferrous sulfate at Korea University Guro and Ansan Hospital from January 1, 2006 to January 1, 2009 were retrospectively analyzed by using the hospital’s medical records on their treatment and hemoglobin levels. Results Thirty-nine patients were enrolled in the treatment success group and eight patients were in the treatment failure group. The cutoff value of serum ferritin for the termination of treatment was 22.95 ng/mL (sensitivity 57.1%, specificity 93.3%). The period that the hemoglobin level was maintained after termination of treatment was not significantly different between the group with a serum ferritin level over 23 ng/mL and the group with a serum ferritin level below 23 ng/mL (Kaplan-Meier curve, p=0.42). The hemoglobin level at the time of treatment termination was a significant prognostic factor for treatment response (p=0.04) in multivariate analysis. Conclusion: The cutoff value of serum ferritin for treatment termination was 22.95 ng/dL, and hemoglobin at the time of treatment termination was a significant prognostic factor (p=0.04). The hazard ratio of the hemoglobin level at the time of treatment termination was 0.27. Further large-scale studies should be undertaken." @default.
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- W2293344453 date "2010-01-01" @default.
- W2293344453 modified "2023-09-27" @default.
- W2293344453 title "The cutoff value of serum ferritin for iron deficiency anemia in determining treatment termination (초)" @default.
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