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• W2293437197 abstract "Marine phytoplankton are responsible for ~50 % of global primary production and encompass a wide range of microorganisms characterized by being phototrophs. Within this group are the marine picocyanobacteria encompassing the phylogenetically closely related genera Synechococcus and Prochlorococcus. Bacteriophage lysis, as well as grazing by eukaryotic protists, play central roles as the major biotic causes of Synechococcus mortality in pelagic systems. However, Synechococcus populations show no extinction, suggesting high rates of production counteract this mortality, or that specific bacteriophage resistance and prey-selectivity mechanisms exist. This thesis set out to determine the molecular basis of cyanophage resistance in marine Synechococcus, using previously isolated cyanophage resistant Synechococcus sp. WH7803 mutants.Whole genome sequencing (WGS) analysis revealed that these cyanophage-resistant Synechococcus sp. WH7803 mutants, as well as a re-sequenced wild type strain, possessed a distinctive mutation profile, with a high number of mutations present in each mutant and with mutations present at a variable frequency. Such a profile is in stark contrast to what was recently found in Prochlorococcus where specific mutations could be identified at 100 % frequency (Avrani et al., 2011). The mutation profile of Synechococcus sp. WH7803 prevented the precise identification of specific genes involved in cyanophage resistance in this strain. This profile was hypothesised to be related to Synechococcus sp. WH7803 being an oligoploid organism, i.e. possessing more than one chromosome copy. Indeed, a qPCR assay that was optimised showed this strain possesses on average four chromosome copies.Subsequent isolation and WGS characterisation of cyanophage resistant mutants from the monoploid strain Synechococcus sp. WH7805 revealed a completely different mutation profile, most similar to that previously described for Prochlorococcus. This identified mutations in a single gene, encoding a possible glycosyltransferase, that were confirmed by Sanger sequencing, as being potentially responsible for cyanophage resistance in this strain." @default.
• W2293437197 created "2016-06-24" @default.
• W2293437197 creator A5051527533 @default.
• W2293437197 date "2015-11-01" @default.
• W2293437197 modified "2023-09-23" @default.
• W2293437197 title "Molecular basis of cyanphage resistance in marine Synechococcus" @default.
• W2293437197 cites W1030697174 @default.
• W2293437197 cites W1038300447 @default.
• W2293437197 cites W137545801 @default.
• W2293437197 cites W1411064714 @default.
• W2293437197 cites W1491092184 @default.
• W2293437197 cites W1492401337 @default.
• W2293437197 cites W1494009434 @default.
• W2293437197 cites W1498596118 @default.
• W2293437197 cites W1500942813 @default.
• W2293437197 cites W1512727593 @default.
• W2293437197 cites W1514768507 @default.
• W2293437197 cites W1519463706 @default.
• W2293437197 cites W1523894467 @default.
• W2293437197 cites W1524026580 @default.
• W2293437197 cites W1524263382 @default.
• W2293437197 cites W1531402328 @default.
• W2293437197 cites W1533809089 @default.
• W2293437197 cites W1544756779 @default.
• W2293437197 cites W1552724685 @default.
• W2293437197 cites W1554809124 @default.
• W2293437197 cites W1556779005 @default.
• W2293437197 cites W1570141112 @default.
• W2293437197 cites W1573209294 @default.
• W2293437197 cites W1573787851 @default.
• W2293437197 cites W1585363264 @default.
• W2293437197 cites W1599047304 @default.
• W2293437197 cites W1602534227 @default.
• W2293437197 cites W1604142172 @default.
• W2293437197 cites W1607492507 @default.
• W2293437197 cites W1615279385 @default.
• W2293437197 cites W1620714331 @default.
• W2293437197 cites W1621072669 @default.
• W2293437197 cites W1726803438 @default.
• W2293437197 cites W1799098265 @default.
• W2293437197 cites W1852463882 @default.
• W2293437197 cites W1855513913 @default.
• W2293437197 cites W1859227820 @default.
• W2293437197 cites W1879821788 @default.
• W2293437197 cites W1881066983 @default.
• W2293437197 cites W1881332855 @default.
• W2293437197 cites W1883691114 @default.
• W2293437197 cites W1924047399 @default.
• W2293437197 cites W1930975169 @default.
• W2293437197 cites W1939886475 @default.
• W2293437197 cites W1960529837 @default.
• W2293437197 cites W1962165774 @default.
• W2293437197 cites W1962861052 @default.
• W2293437197 cites W1963530707 @default.
• W2293437197 cites W1964027624 @default.
• W2293437197 cites W1964783419 @default.
• W2293437197 cites W1966273500 @default.
• W2293437197 cites W1966952999 @default.
• W2293437197 cites W1967667349 @default.
• W2293437197 cites W1967674344 @default.
• W2293437197 cites W1967725603 @default.
• W2293437197 cites W1969715054 @default.
• W2293437197 cites W1971184497 @default.
• W2293437197 cites W1975139181 @default.
• W2293437197 cites W1977293483 @default.
• W2293437197 cites W1978126958 @default.
• W2293437197 cites W1978886837 @default.
• W2293437197 cites W1979047200 @default.
• W2293437197 cites W1980427104 @default.
• W2293437197 cites W1980754431 @default.
• W2293437197 cites W1981069592 @default.
• W2293437197 cites W1983725736 @default.
• W2293437197 cites W1984640298 @default.
• W2293437197 cites W1985677799 @default.
• W2293437197 cites W1987218857 @default.
• W2293437197 cites W1988016622 @default.
• W2293437197 cites W1988691705 @default.
• W2293437197 cites W1988853594 @default.
• W2293437197 cites W1988967448 @default.
• W2293437197 cites W1989512904 @default.
• W2293437197 cites W1990118801 @default.
• W2293437197 cites W1990405522 @default.
• W2293437197 cites W1991416140 @default.
• W2293437197 cites W1991604124 @default.
• W2293437197 cites W1993941956 @default.
• W2293437197 cites W1994995128 @default.
• W2293437197 cites W1995614275 @default.
• W2293437197 cites W1995855352 @default.
• W2293437197 cites W1996165930 @default.
• W2293437197 cites W1996477519 @default.
• W2293437197 cites W1996488480 @default.
• W2293437197 cites W1996659470 @default.
• W2293437197 cites W1996758777 @default.
• W2293437197 cites W1997329740 @default.
• W2293437197 cites W1998351336 @default.
• W2293437197 cites W1998699639 @default.
• W2293437197 cites W1998878910 @default.
• W2293437197 cites W2000946245 @default.
• W2293437197 cites W2001886483 @default.
• W2293437197 cites W2001959084 @default.

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