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• W2293666614 endingPage "G789" @default.
• W2293666614 startingPage "G776" @default.
• W2293666614 abstract "Dietary lipids are transported from the intestine through contractile lymphatics. Chronic lipid loads can adversely affect lymphatic function. However, the acute lymphatic pump response in the mesentery to a postprandial lipid meal has gone unexplored. In this study, we used the rat mesenteric collecting vessel as an in vivo model to quantify the effect of lipoproteins on vessel function. Lipid load was continuously monitored by using the intensity of a fluorescent fatty-acid analog, which we infused along with a fat emulsion through a duodenal cannula. The vessel contractility was simultaneously quantified. We demonstrated for the first time that collecting lymphatic vessels respond to an acute lipid load by reducing pump function. High lipid levels decreased contraction frequency and amplitude. We also showed a strong tonic response through a reduction in the end-diastolic and systolic diameters. We further characterized the changes in flow rate and viscosity and showed that both increase postprandially. In addition, shear-mediated Ca 2+ signaling in lymphatic endothelial cells differed when cultured with lipoproteins. Together these results show that the in vivo response could be both shear and lipid mediated and provide the first evidence that high postprandial lipid has an immediate negative effect on lymphatic function even in the acute setting." @default.
• W2293666614 created "2016-06-24" @default.
• W2293666614 creator A5007118437 @default.
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• W2293666614 creator A5049748904 @default.
• W2293666614 creator A5071773288 @default.
• W2293666614 date "2016-05-15" @default.
• W2293666614 modified "2023-10-16" @default.
• W2293666614 title "Postprandial lymphatic pump function after a high-fat meal: a characterization of contractility, flow, and viscosity" @default.
• W2293666614 cites W113825789 @default.
• W2293666614 cites W1497095586 @default.
• W2293666614 cites W1526118780 @default.
• W2293666614 cites W1531695174 @default.
• W2293666614 cites W1550865610 @default.
• W2293666614 cites W177024317 @default.
• W2293666614 cites W1879954941 @default.
• W2293666614 cites W1892317708 @default.
• W2293666614 cites W1897243740 @default.
• W2293666614 cites W1920988115 @default.
• W2293666614 cites W1966922276 @default.
• W2293666614 cites W1968237864 @default.
• W2293666614 cites W1970920203 @default.
• W2293666614 cites W1972659566 @default.
• W2293666614 cites W1984495906 @default.
• W2293666614 cites W1988248351 @default.
• W2293666614 cites W1993794497 @default.
• W2293666614 cites W1995225946 @default.
• W2293666614 cites W1996527882 @default.
• W2293666614 cites W1997944980 @default.
• W2293666614 cites W2000334664 @default.
• W2293666614 cites W2004851132 @default.
• W2293666614 cites W2005381807 @default.
• W2293666614 cites W2011523889 @default.
• W2293666614 cites W2015575081 @default.
• W2293666614 cites W2019543527 @default.
• W2293666614 cites W2025693270 @default.
• W2293666614 cites W2026385925 @default.
• W2293666614 cites W2032783715 @default.
• W2293666614 cites W2038581980 @default.
• W2293666614 cites W2039119127 @default.
• W2293666614 cites W2039904257 @default.
• W2293666614 cites W2042629182 @default.
• W2293666614 cites W2046563057 @default.
• W2293666614 cites W2047486925 @default.
• W2293666614 cites W2049481178 @default.
• W2293666614 cites W2057440460 @default.
• W2293666614 cites W2058909179 @default.
• W2293666614 cites W2060488986 @default.
• W2293666614 cites W2067150213 @default.
• W2293666614 cites W2068581049 @default.
• W2293666614 cites W2075719343 @default.
• W2293666614 cites W2081523471 @default.
• W2293666614 cites W2082754108 @default.
• W2293666614 cites W2084085941 @default.
• W2293666614 cites W2090956293 @default.
• W2293666614 cites W2101192212 @default.
• W2293666614 cites W2101904915 @default.
• W2293666614 cites W2101908446 @default.
• W2293666614 cites W2106245989 @default.
• W2293666614 cites W2111664931 @default.
• W2293666614 cites W2111857958 @default.
• W2293666614 cites W2113265524 @default.
• W2293666614 cites W2114695967 @default.
• W2293666614 cites W2115392273 @default.
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• W2293666614 cites W2115734659 @default.
• W2293666614 cites W2115954005 @default.
• W2293666614 cites W2117107881 @default.
• W2293666614 cites W2117767336 @default.
• W2293666614 cites W2118313918 @default.
• W2293666614 cites W2118722193 @default.
• W2293666614 cites W2120551200 @default.
• W2293666614 cites W2124073510 @default.
• W2293666614 cites W2132454600 @default.
• W2293666614 cites W2133146268 @default.
• W2293666614 cites W2136338608 @default.
• W2293666614 cites W2137753785 @default.
• W2293666614 cites W2144204589 @default.
• W2293666614 cites W2160157834 @default.
• W2293666614 cites W2164115669 @default.
• W2293666614 cites W2168763296 @default.
• W2293666614 cites W2186296848 @default.
• W2293666614 cites W2198272944 @default.
• W2293666614 cites W2212497817 @default.
• W2293666614 cites W2253314035 @default.
• W2293666614 cites W2261393776 @default.
• W2293666614 cites W2272732281 @default.
• W2293666614 cites W2290891977 @default.
• W2293666614 cites W2330854548 @default.
• W2293666614 cites W2417609713 @default.
• W2293666614 cites W4236709343 @default.
• W2293666614 cites W4255376078 @default.
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• W2293666614 doi "https://doi.org/10.1152/ajpgi.00318.2015" @default.
• W2293666614 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4888550" @default.
• W2293666614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26968208" @default.

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