Matches in SemOpenAlex for { <https://semopenalex.org/work/W2293888843> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2293888843 endingPage "8551" @default.
- W2293888843 startingPage "8551" @default.
- W2293888843 abstract "8551 NWTS - 5 was a multi-institutional clinical trial for patients less than 16 years of age at diagnosis with specific renal neoplasms who were diagnosed between August 1, 1995 and May 31, 2002. A uniform approach to the treatment of patients with relapse was employed. 72 patients who relapsed after immediate nephrectomy (stages I and II), initial chemotherapy with vincristine and actinomycin D and no radiation therapy were registered on stratum B of the NWTS-5 Relapse protocol. Four patients were not evaluable: one due to insufficient data and 3 due to major protocol violations. Among the 68 remaining patients, 5 with bilateral Wilms tumor at diagnosis, 3 who developed a contralateral relapse and 1 with persistent disease were not included in this analysis. Relapse treatment included surgical excision, when feasible, radiation therapy and alternating courses of vincristine, doxorubicin and cyclophosphamide and etoposide and cyclophosphamide. The most frequent toxicities were hematological. These results demonstrate that a significant proportion of children with Wilms tumor who relapse after initial treatment with vincristine and actinomycin D can be successfully re-treated. Author Disclosure Results by Site of Relapse Site of Relapse Number of Patients Number of Second Events 4-year EFS (%) Number of Deaths 4-year Survival (%) All 59 15 69.1 10 82.2 Operative bed lung other sites 18 2 77.8 2 88.0 Liver 1 1 0.0 0 0.0 Abdomen or pelvis other sites 6 1 66.7 0 0.0 Lung only 31 9 67.8 7 81.0 Lung and other 2 1 50.0 1 50.0 Other 1 0 - 0 - No significant financial relationships to disclose." @default.
- W2293888843 created "2016-06-24" @default.
- W2293888843 creator A5001281739 @default.
- W2293888843 creator A5029977137 @default.
- W2293888843 creator A5058418326 @default.
- W2293888843 creator A5060037035 @default.
- W2293888843 creator A5071660818 @default.
- W2293888843 creator A5074349523 @default.
- W2293888843 creator A5081276533 @default.
- W2293888843 creator A5084961498 @default.
- W2293888843 creator A5086900692 @default.
- W2293888843 creator A5087530499 @default.
- W2293888843 date "2005-06-01" @default.
- W2293888843 modified "2023-09-25" @default.
- W2293888843 title "Treatment of Wilms tumor relapsing after initial treatment with vincristine and actinomycin D. A report from the National Wilms Tumor Study (NWTS) Group" @default.
- W2293888843 doi "https://doi.org/10.1200/jco.2005.23.16_suppl.8551" @default.
- W2293888843 hasPublicationYear "2005" @default.
- W2293888843 type Work @default.
- W2293888843 sameAs 2293888843 @default.
- W2293888843 citedByCount "0" @default.
- W2293888843 crossrefType "journal-article" @default.
- W2293888843 hasAuthorship W2293888843A5001281739 @default.
- W2293888843 hasAuthorship W2293888843A5029977137 @default.
- W2293888843 hasAuthorship W2293888843A5058418326 @default.
- W2293888843 hasAuthorship W2293888843A5060037035 @default.
- W2293888843 hasAuthorship W2293888843A5071660818 @default.
- W2293888843 hasAuthorship W2293888843A5074349523 @default.
- W2293888843 hasAuthorship W2293888843A5081276533 @default.
- W2293888843 hasAuthorship W2293888843A5084961498 @default.
- W2293888843 hasAuthorship W2293888843A5086900692 @default.
- W2293888843 hasAuthorship W2293888843A5087530499 @default.
- W2293888843 hasConcept C126322002 @default.
- W2293888843 hasConcept C141071460 @default.
- W2293888843 hasConcept C2775999222 @default.
- W2293888843 hasConcept C2776694085 @default.
- W2293888843 hasConcept C2776755627 @default.
- W2293888843 hasConcept C2778119113 @default.
- W2293888843 hasConcept C2779429289 @default.
- W2293888843 hasConcept C2780091579 @default.
- W2293888843 hasConcept C2780227381 @default.
- W2293888843 hasConcept C509974204 @default.
- W2293888843 hasConcept C71924100 @default.
- W2293888843 hasConceptScore W2293888843C126322002 @default.
- W2293888843 hasConceptScore W2293888843C141071460 @default.
- W2293888843 hasConceptScore W2293888843C2775999222 @default.
- W2293888843 hasConceptScore W2293888843C2776694085 @default.
- W2293888843 hasConceptScore W2293888843C2776755627 @default.
- W2293888843 hasConceptScore W2293888843C2778119113 @default.
- W2293888843 hasConceptScore W2293888843C2779429289 @default.
- W2293888843 hasConceptScore W2293888843C2780091579 @default.
- W2293888843 hasConceptScore W2293888843C2780227381 @default.
- W2293888843 hasConceptScore W2293888843C509974204 @default.
- W2293888843 hasConceptScore W2293888843C71924100 @default.
- W2293888843 hasIssue "16_suppl" @default.
- W2293888843 hasLocation W22938888431 @default.
- W2293888843 hasOpenAccess W2293888843 @default.
- W2293888843 hasPrimaryLocation W22938888431 @default.
- W2293888843 hasRelatedWork W1994615521 @default.
- W2293888843 hasRelatedWork W2027086316 @default.
- W2293888843 hasRelatedWork W2029724900 @default.
- W2293888843 hasRelatedWork W2047930003 @default.
- W2293888843 hasRelatedWork W2121694206 @default.
- W2293888843 hasRelatedWork W2230522317 @default.
- W2293888843 hasRelatedWork W2252336101 @default.
- W2293888843 hasRelatedWork W2412181118 @default.
- W2293888843 hasRelatedWork W2412856609 @default.
- W2293888843 hasRelatedWork W2416766314 @default.
- W2293888843 hasVolume "23" @default.
- W2293888843 isParatext "false" @default.
- W2293888843 isRetracted "false" @default.
- W2293888843 magId "2293888843" @default.
- W2293888843 workType "article" @default.