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- W2294084309 abstract "In vivo multi-target and selective concentration monitoring of neurotransmitters can help to unravel the brain chemical complex signaling interplay. This paper presents a dedicated integrated potentiostat transducer circuit and its selective electrode interface. A custom 2-electrode time-based potentiostat circuit was fabricated with 0.13 μm CMOS technology and provides a wide dynamic input current range of 20 pA to 600 nA with 56 μ W, for a minimum sampling frequency of 1.25 kHz. A multi-working electrode chip is functionalized with carbon nanotubes (CNT)-based chemical coatings that offer high sensitivity and selectivity towards electroactive dopamine and non-electroactive glutamate. The prototype was experimentally tested with different concentrations levels of both neurotransmitter types, and results were similar to measurements with a commercially available potentiostat. This paper validates the functionality of the proposed biosensor, and demonstrates its potential for the selective detection of a large number of neurochemicals." @default.
- W2294084309 created "2016-06-24" @default.
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- W2294084309 date "2016-06-01" @default.
- W2294084309 modified "2023-10-01" @default.
- W2294084309 title "A CMOS Amperometric System for Multi-Neurotransmitter Detection" @default.
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- W2294084309 doi "https://doi.org/10.1109/tbcas.2015.2490225" @default.
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