FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2294828136> ?p ?o ?g. }

• W2294828136 endingPage "e0004498" @default.
• W2294828136 startingPage "e0004498" @default.
• W2294828136 abstract "The scale and geographical distribution of the current outbreak in West Africa raised doubts as to the effectiveness of established methods of control. Ebola Virus Disease (EVD) was first detected in Sierra Leone in May 2014 in Kailahun district. Despite high case numbers elsewhere in the country, transmission was eliminated in the district by December 2014. We describe interventions underpinning successful EVD control in Kailahun and implications for EVD control in other areas.Internal service data and published reports from response agencies were analysed to describe the structure and type of response activities, EVD case numbers and epidemic characteristics. This included daily national situation reports and District-level data and reports of the Sierra Leone Ministry of Health and Sanitation, and Médecins Sans Frontières (MSF) patient data and internal epidemiological reports. We used EVD case definitions provided by the World Health Organisation over the course of the outbreak. Characteristics assessed included level of response activities and epidemiological features such as reported exposure (funeral-related or not), time interval between onset of illness and admission to the EVD Management Centre (EMC), work-related exposures (health worker or not) and mortality. We compared these characteristics between two time periods--June to July (the early period of response), and August to December (when coverage and quality of response had improved). A stochastic model was used to predict case numbers per generation with different numbers of beds and a varying percentage of community cases detected.There were 652 probable/confirmed EVD cases from June-December 2014 in Kailahun. An EMC providing patient care opened in June. By August 2014 an integrated detection, treatment, and prevention strategy was in place across the district catchment zone. From June-July to August-December 2014 surveillance and contact tracing staff increased from 1.0 to 8.8 per confirmed EVD case, EMC capacity increased from 32 to 100 beds, the number of burial teams doubled, and health promotion activities increased in coverage. These improvements in response were associated with the following changes between the same periods: the proportion of confirmed/probable cases admitted to the EMC increased from 35% to 83% (χ(2) p-value<0·001), the proportion of confirmed patients admitted to the EMC <3 days of symptom onset increased from 19% to 37% (χ(2) p-value <0·001), and reported funeral contact in those admitted decreased from 33% to 16% (χ(2) p-value <0·001). Mathematical modelling confirmed the importance of both patient management capacity and surveillance and contact tracing for EVD control.Our findings demonstrate that control of EVD can be achieved using established interventions based on identification and appropriate management of those who are at risk of and develop EVD, including in the context of ongoing transmission in surrounding regions. Key attributes in achieving control were sufficient patient care capacity (including admission to specialist facilities of suspect and probable cases for assessment), integrated with adequate staffing and resourcing of community-based case detection and prevention activities. The response structure and coverage targets we present are of value in informing effective control in current and future EVD outbreaks." @default.
• W2294828136 created "2016-06-24" @default.
• W2294828136 creator A5001116608 @default.
• W2294828136 creator A5011298464 @default.
• W2294828136 creator A5015297485 @default.
• W2294828136 creator A5019717829 @default.
• W2294828136 creator A5024680340 @default.
• W2294828136 creator A5025480549 @default.
• W2294828136 creator A5029122036 @default.
• W2294828136 creator A5035703530 @default.
• W2294828136 creator A5037560809 @default.
• W2294828136 creator A5047571018 @default.
• W2294828136 creator A5051652706 @default.
• W2294828136 creator A5053264166 @default.
• W2294828136 creator A5062675823 @default.
• W2294828136 creator A5062928362 @default.
• W2294828136 creator A5064916639 @default.
• W2294828136 creator A5065781999 @default.
• W2294828136 creator A5085473020 @default.
• W2294828136 creator A5090096194 @default.
• W2294828136 date "2016-03-09" @default.
• W2294828136 modified "2023-10-14" @default.
• W2294828136 title "Successful Control of Ebola Virus Disease: Analysis of Service Based Data from Rural Sierra Leone" @default.
• W2294828136 cites W131458748 @default.
• W2294828136 cites W1880262857 @default.
• W2294828136 cites W1964547832 @default.
• W2294828136 cites W2027035827 @default.
• W2294828136 cites W2033832533 @default.
• W2294828136 cites W2034362332 @default.
• W2294828136 cites W2103390652 @default.
• W2294828136 cites W2105084778 @default.
• W2294828136 cites W2106363305 @default.
• W2294828136 cites W2106522948 @default.
• W2294828136 cites W2163081652 @default.
• W2294828136 cites W2325644423 @default.
• W2294828136 cites W2400532519 @default.
• W2294828136 cites W4210710163 @default.
• W2294828136 cites W585575935 @default.
• W2294828136 doi "https://doi.org/10.1371/journal.pntd.0004498" @default.
• W2294828136 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4784943" @default.
• W2294828136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26959413" @default.
• W2294828136 hasPublicationYear "2016" @default.
• W2294828136 type Work @default.
• W2294828136 sameAs 2294828136 @default.
• W2294828136 citedByCount "22" @default.
• W2294828136 countsByYear W22948281362017 @default.
• W2294828136 countsByYear W22948281362018 @default.
• W2294828136 countsByYear W22948281362019 @default.
• W2294828136 countsByYear W22948281362020 @default.
• W2294828136 countsByYear W22948281362021 @default.
• W2294828136 countsByYear W22948281362022 @default.
• W2294828136 crossrefType "journal-article" @default.
• W2294828136 hasAuthorship W2294828136A5001116608 @default.
• W2294828136 hasAuthorship W2294828136A5011298464 @default.
• W2294828136 hasAuthorship W2294828136A5015297485 @default.
• W2294828136 hasAuthorship W2294828136A5019717829 @default.
• W2294828136 hasAuthorship W2294828136A5024680340 @default.
• W2294828136 hasAuthorship W2294828136A5025480549 @default.
• W2294828136 hasAuthorship W2294828136A5029122036 @default.
• W2294828136 hasAuthorship W2294828136A5035703530 @default.
• W2294828136 hasAuthorship W2294828136A5037560809 @default.
• W2294828136 hasAuthorship W2294828136A5047571018 @default.
• W2294828136 hasAuthorship W2294828136A5051652706 @default.
• W2294828136 hasAuthorship W2294828136A5053264166 @default.
• W2294828136 hasAuthorship W2294828136A5062675823 @default.
• W2294828136 hasAuthorship W2294828136A5062928362 @default.
• W2294828136 hasAuthorship W2294828136A5064916639 @default.
• W2294828136 hasAuthorship W2294828136A5065781999 @default.
• W2294828136 hasAuthorship W2294828136A5085473020 @default.
• W2294828136 hasAuthorship W2294828136A5090096194 @default.
• W2294828136 hasBestOaLocation W22948281361 @default.
• W2294828136 hasConcept C107130276 @default.
• W2294828136 hasConcept C113162765 @default.
• W2294828136 hasConcept C116675565 @default.
• W2294828136 hasConcept C126322002 @default.
• W2294828136 hasConcept C142724271 @default.
• W2294828136 hasConcept C144024400 @default.
• W2294828136 hasConcept C149923435 @default.
• W2294828136 hasConcept C159047783 @default.
• W2294828136 hasConcept C159110408 @default.
• W2294828136 hasConcept C27415008 @default.
• W2294828136 hasConcept C2777469322 @default.
• W2294828136 hasConcept C2779134260 @default.
• W2294828136 hasConcept C2780151969 @default.
• W2294828136 hasConcept C3008058167 @default.
• W2294828136 hasConcept C3018567284 @default.
• W2294828136 hasConcept C45355965 @default.
• W2294828136 hasConcept C524204448 @default.
• W2294828136 hasConcept C71924100 @default.
• W2294828136 hasConcept C99454951 @default.
• W2294828136 hasConceptScore W2294828136C107130276 @default.
• W2294828136 hasConceptScore W2294828136C113162765 @default.
• W2294828136 hasConceptScore W2294828136C116675565 @default.
• W2294828136 hasConceptScore W2294828136C126322002 @default.
• W2294828136 hasConceptScore W2294828136C142724271 @default.
• W2294828136 hasConceptScore W2294828136C144024400 @default.
• W2294828136 hasConceptScore W2294828136C149923435 @default.
• W2294828136 hasConceptScore W2294828136C159047783 @default.

• next