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• W2295803168 abstract "A qualitative method was developed for describing and comparing populations and subgroups in relation to a world standard for median age and variability of menarche cumulative fertility and menopause. The method provided a means for converting the median ages and the standard deviations for the 3 menstrual events observed in a specific population into percentile rankings in respect to the world distribution of median age and standard deviation scores for these events. The method was tested using data from 3 populations. These populations were the US the Dobe]Kung of Botswana and the Micronesians of Yap. A modified bioassay model was used. The bioassay model was initially developed for the purpose of evaluating the responses of organisms to different doses of a substance. In the present application of the model the responses were the occurrences of the 3 menstrual cycle events for the women in each population and the dose levels were the ages at which the women experienced the 3 events. Attainment lines for menarche cumulative fertility and menopause for each population were derived by regressing probits on the x scale defined as the logarithm of age from conception. The attainment lines were then tested for parallelism. That is the 3 events were assessed in reference to whether or not they could be viewed as successively graded responses of the endometrium tissue. The cumulative fertility lines were not fully explainable as endometrium responses however the lines in each population had a standard deviation in x units which approximated a simple multiple of a common standard deviation formenarche and menopause. These findings were then used to construct a world standard for the 3 events. Previously compiled data on 124 societies was used to identify the worldwide median ages and variability for menarche and menopause. Data from the US the Dobe]Kung and the Micronesians were further analyzed in reference to this world standard. For the US the median age at menarche ranked in the 14th percentile of the world distribution and was therefore early compared to most of the rest of the world. Median age at menopause was late compared to other populations and ranked at the 90th percentile. The US timespan from menarche to menopause was long compared to most other populations (98th percentile level). Median age of fertility was very low (3rd percentile). Thus US women had a longer reproductive span than women in most other countries but US women restricted their fertility to a small segment of this timespan. In the US there was a moderate degree of variability around the median age at menarche (59th percentile) and menopause (59th percentile) and very little variability around the median age of fertility (2nd percentile). For the Dobe]Kung median age percentile levels were 96th for menarche 79th for menopause 22nd for the timespan between menarche and menopause and 55th for fertility. The respective percentile levels for the Micronesians were 81st 69th 47th and 14th. The degree of deviation from the median ages for the 3 events was relatively low for the Dobe]Kung and relatively high for the Micronesians." @default.
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• W2295803168 title "The timing and variability of menarche, cumulative fertility and menopause: a symmetrical and parsimonious bioassay model." @default.
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