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- W2295909319 abstract "We hypothesize that the attenuated hypertrophic response in old mouse muscle is (1) partly due to a reduced capillarization and angiogenesis, which is (2) accompanied by a reduced oxidative capacity and fatigue resistance in old control and overloaded muscles, that (3) can be rescued by the antioxidant resveratrol. To investigate this, the hypertrophic response, capillarization, oxidative capacity, and fatigue resistance of m. plantaris were compared in 9- and 25-month-old non-treated and 25-month-old resveratrol-treated mice. Overload increased the local capillary-to-fiber ratio less in old (15 %) than in adult (59 %) muscle (P < 0.05). Although muscles of old mice had a higher succinate dehydrogenase (SDH) activity (P < 0.05) and a slower fiber type profile (P < 0.05), the isometric fatigue resistance was similar in 9- and 25-month-old mice. In both age groups, the fatigue resistance was increased to the same extent after overload (P < 0.01), without a significant change in SDH activity, but an increased capillary density (P < 0.05). Attenuated angiogenesis during overload may contribute to the attenuated hypertrophic response in old age. Neither was rescued by resveratrol supplementation. Changes in fatigue resistance with overload and aging were dissociated from changes in SDH activity, but paralleled those in capillarization. This suggests that capillarization plays a more important role in fatigue resistance than oxidative capacity." @default.
- W2295909319 created "2016-06-24" @default.
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- W2295909319 date "2016-03-12" @default.
- W2295909319 modified "2023-10-17" @default.
- W2295909319 title "Blunted angiogenesis and hypertrophy are associated with increased fatigue resistance and unchanged aerobic capacity in old overloaded mouse muscle" @default.
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- W2295909319 cites W1707476148 @default.
- W2295909319 cites W1964771425 @default.
- W2295909319 cites W1965210871 @default.
- W2295909319 cites W1970658538 @default.
- W2295909319 cites W1980335627 @default.
- W2295909319 cites W1983551439 @default.
- W2295909319 cites W1983905681 @default.
- W2295909319 cites W1985130783 @default.
- W2295909319 cites W1990567121 @default.
- W2295909319 cites W1992610736 @default.
- W2295909319 cites W1997961280 @default.
- W2295909319 cites W2002120580 @default.
- W2295909319 cites W2005375864 @default.
- W2295909319 cites W2007541295 @default.
- W2295909319 cites W2009812367 @default.
- W2295909319 cites W2011398127 @default.
- W2295909319 cites W2014146197 @default.
- W2295909319 cites W2018318803 @default.
- W2295909319 cites W2018411968 @default.
- W2295909319 cites W2031619656 @default.
- W2295909319 cites W2033588339 @default.
- W2295909319 cites W2039773817 @default.
- W2295909319 cites W2044857579 @default.
- W2295909319 cites W2045672376 @default.
- W2295909319 cites W2054511417 @default.
- W2295909319 cites W2055006202 @default.
- W2295909319 cites W2063104169 @default.
- W2295909319 cites W2070221644 @default.
- W2295909319 cites W2085604781 @default.
- W2295909319 cites W2088442294 @default.
- W2295909319 cites W2089950181 @default.
- W2295909319 cites W2092868937 @default.
- W2295909319 cites W2097408175 @default.
- W2295909319 cites W2097443151 @default.
- W2295909319 cites W2107544153 @default.
- W2295909319 cites W2107689453 @default.
- W2295909319 cites W2108953036 @default.
- W2295909319 cites W2112991269 @default.
- W2295909319 cites W2114726782 @default.
- W2295909319 cites W2121443655 @default.
- W2295909319 cites W2121486568 @default.
- W2295909319 cites W2122927067 @default.
- W2295909319 cites W2123064842 @default.
- W2295909319 cites W2124759522 @default.
- W2295909319 cites W2132481390 @default.
- W2295909319 cites W2133758469 @default.
- W2295909319 cites W2134337709 @default.
- W2295909319 cites W2138134399 @default.
- W2295909319 cites W2138806361 @default.
- W2295909319 cites W2144530325 @default.
- W2295909319 cites W2144600435 @default.
- W2295909319 cites W2146026176 @default.
- W2295909319 cites W2155130652 @default.
- W2295909319 cites W2157585206 @default.
- W2295909319 cites W2158449289 @default.
- W2295909319 cites W2160682517 @default.
- W2295909319 cites W2162570377 @default.
- W2295909319 cites W2166926510 @default.
- W2295909319 cites W2167535069 @default.
- W2295909319 cites W2180364688 @default.
- W2295909319 cites W2182329462 @default.
- W2295909319 cites W220593608 @default.
- W2295909319 cites W2286278798 @default.
- W2295909319 cites W2321613972 @default.
- W2295909319 cites W250805346 @default.
- W2295909319 cites W29328053 @default.
- W2295909319 cites W4240654071 @default.
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- W2295909319 doi "https://doi.org/10.1007/s11357-016-9894-1" @default.
- W2295909319 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5006008" @default.
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- W2295909319 hasPublicationYear "2016" @default.
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