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• W2295982294 startingPage "2276" @default.
• W2295982294 abstract "Chronic alcohol use is associated with declines in gray matter (GM) volume, as is the normal aging process. Less apparent, however, is how the interaction between aging and heavy alcohol use affects changes in GM across the lifespan. There is some evidence that women are more vulnerable to the negative effects of alcohol use on GM than men. In the current study, we examined whether localized GM was related to measures of alcohol use disorder (e.g., AUDIT score) in a large sample (N = 436) of participants, ages 18-55 years, with a range of disease severity, using both voxel-based morphometry (VBM) and surface-based morphometry (SBM). We also explored whether GM associations with alcohol use disorder (AUD) severity are moderated by sex and age. Results showed significant negative associations between AUD severity and GM volume throughout temporal, parietal, frontal, and occipital lobes. Women showed more negative effects of alcohol use than men for cortical thickness in left orbitofrontal cortex, but evidence for increased vulnerability based on sex was limited overall. Similarly, a specific age by alcohol use interaction was observed for volume of right insula, but other regional or global interactions were not statistically supported. However, significant negative associations between heavy alcohol use and GM volumes were observed as early as 18-25 years. These findings support that alcohol has deleterious effects on global and regional GM above and beyond age, and, of particular importance, that regional associations emerge in early adulthood. Hum Brain Mapp 37:2276-2292, 2016. © 2016 Wiley Periodicals, Inc." @default.
• W2295982294 created "2016-06-24" @default.
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• W2295982294 date "2016-03-07" @default.
• W2295982294 modified "2023-10-12" @default.
• W2295982294 title "Negative and interactive effects of sex, aging, and alcohol abuse on gray matter morphometry" @default.
• W2295982294 cites W1475474724 @default.
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• W2295982294 cites W1515126555 @default.
• W2295982294 cites W1585069912 @default.
• W2295982294 cites W1965429322 @default.
• W2295982294 cites W1969064591 @default.
• W2295982294 cites W1971548649 @default.
• W2295982294 cites W1971954061 @default.
• W2295982294 cites W1972229456 @default.
• W2295982294 cites W1975458997 @default.
• W2295982294 cites W1976622369 @default.
• W2295982294 cites W1984111997 @default.
• W2295982294 cites W1989494781 @default.
• W2295982294 cites W1995143272 @default.
• W2295982294 cites W1998138099 @default.
• W2295982294 cites W2003775449 @default.
• W2295982294 cites W2004293194 @default.
• W2295982294 cites W2009577585 @default.
• W2295982294 cites W2012721918 @default.
• W2295982294 cites W2018639131 @default.
• W2295982294 cites W2021852270 @default.
• W2295982294 cites W2031425398 @default.
• W2295982294 cites W2034139611 @default.
• W2295982294 cites W2036495407 @default.
• W2295982294 cites W2038543194 @default.
• W2295982294 cites W2038648182 @default.
• W2295982294 cites W2044724840 @default.
• W2295982294 cites W2048163838 @default.
• W2295982294 cites W2058027980 @default.
• W2295982294 cites W2060089949 @default.
• W2295982294 cites W2062956681 @default.
• W2295982294 cites W2066313761 @default.
• W2295982294 cites W2067165730 @default.
• W2295982294 cites W2067975928 @default.
• W2295982294 cites W2067990867 @default.
• W2295982294 cites W2071210438 @default.
• W2295982294 cites W2072500831 @default.
• W2295982294 cites W2077844144 @default.
• W2295982294 cites W2089692573 @default.
• W2295982294 cites W2091910506 @default.
• W2295982294 cites W2093830143 @default.
• W2295982294 cites W2101846840 @default.
• W2295982294 cites W2103481737 @default.
• W2295982294 cites W2105086806 @default.
• W2295982294 cites W2107287771 @default.
• W2295982294 cites W2110208125 @default.
• W2295982294 cites W2110608362 @default.
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• W2295982294 cites W2117264727 @default.
• W2295982294 cites W2117808207 @default.
• W2295982294 cites W2118421222 @default.
• W2295982294 cites W2119848633 @default.
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• W2295982294 cites W2126999739 @default.
• W2295982294 cites W2131675069 @default.
• W2295982294 cites W2136500228 @default.
• W2295982294 cites W2139898307 @default.
• W2295982294 cites W2140142910 @default.
• W2295982294 cites W2145601914 @default.
• W2295982294 cites W2147597108 @default.
• W2295982294 cites W2149331480 @default.
• W2295982294 cites W2151130155 @default.
• W2295982294 cites W2151721316 @default.
• W2295982294 cites W2153296314 @default.
• W2295982294 cites W2155963684 @default.
• W2295982294 cites W2156133811 @default.
• W2295982294 cites W2157270343 @default.
• W2295982294 cites W2157848968 @default.
• W2295982294 cites W2160800897 @default.
• W2295982294 cites W2161198625 @default.
• W2295982294 cites W2164324679 @default.
• W2295982294 cites W2164334953 @default.
• W2295982294 cites W2421079488 @default.
• W2295982294 cites W4235691060 @default.
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• W2295982294 doi "https://doi.org/10.1002/hbm.23172" @default.
• W2295982294 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4867295" @default.
• W2295982294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26947584" @default.
• W2295982294 hasPublicationYear "2016" @default.
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