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- W2296202250 abstract "Abstract pH of microalgal cultures increases with cell growth particularly in nitrate-based growth media, which requires chemical pH adjustment such as CO 2 injection to prevent ‘culture crash’. The CO 2 injection however, is expensive and technically challenging in large-scale cultures. This study reports a unique and practical pH control mechanism through a new medium formulation with nutrient and proton balances, called B-8 medium. Comparison of B-8 to a common nutrient-balanced M-8 medium for growing Chlorella vulgaris showed that B-8 stabilized pH, supported 10–20% more biomass and was 60% less expensive than M-8. The scalability of the B-8 medium to facilitate pH control was further demonstrated by achieving pH stability in 4.8 L photobioreactor cultures without additional chemical buffering. This demonstrates for the first time, that practical and scalable pH control in high-density microalgal cultures can be achieved through growth medium optimization for nutrient and proton balances—an easier and more economical alternative to those achieved chemically." @default.
- W2296202250 created "2016-06-24" @default.
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- W2296202250 date "2016-06-01" @default.
- W2296202250 modified "2023-10-03" @default.
- W2296202250 title "Proton and nutrient balanced medium for scalable, practical pH control in high-density Chlorella vulgaris cultures" @default.
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- W2296202250 doi "https://doi.org/10.1016/j.algal.2016.02.031" @default.
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