Matches in SemOpenAlex for { <https://semopenalex.org/work/W2296235101> ?p ?o ?g. }
- W2296235101 abstract "Titin is a giant scaffold protein with multiple functions in striated muscle physiology. Due to the elastic I-band domains and the filament-like integration in the half-sarcomere titin is an important factor for sarcomere assembly and serves as an adaptable molecular spring that determines myofilament distensibility. Protein-interactions e.g., with muscle ankyrin repeat proteins or muscle LIM-protein link titin to hypertrophic signaling and via p62 and Muscle Ring Finger proteins to mechanisms that control protein quality control. This review summarizes our current knowledge on titin as a central node for exercise-induced mechanosignaling and remodeling and further highlights the pathophysiological implications." @default.
- W2296235101 created "2016-06-24" @default.
- W2296235101 creator A5085964464 @default.
- W2296235101 creator A5091166926 @default.
- W2296235101 date "2016-03-01" @default.
- W2296235101 modified "2023-10-17" @default.
- W2296235101 title "Titin, a Central Mediator for Hypertrophic Signaling, Exercise-Induced Mechanosignaling and Skeletal Muscle Remodeling" @default.
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- W2296235101 doi "https://doi.org/10.3389/fphys.2016.00076" @default.
- W2296235101 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4771757" @default.
- W2296235101 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26973541" @default.
- W2296235101 hasPublicationYear "2016" @default.
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